Thromb Haemost 1999; 81(04): 659-660
DOI: 10.1055/s-0037-1614543
Letters to the Editor
Schattauer GmbH

Fibrinogen Is not an Additional Risk Factor of Thromboembolic Disease in Factor V Leiden Patients

Sandrine Billon
1   From the Molecular Genetic Laboratory, CHU Morvan, Boulevard Tanguy Prigent, Brest, France
2   Hematology Department, C.H.U Morvan. and the Centre de Biogénétique, Brest, France
,
Martine Escoffre-Barbe
2   Hematology Department, C.H.U Morvan. and the Centre de Biogénétique, Brest, France
,
Bernard Mercier
1   From the Molecular Genetic Laboratory, CHU Morvan, Boulevard Tanguy Prigent, Brest, France
3   E.T.S.B.O., Brest, France
,
Jean François Abgrall
2   Hematology Department, C.H.U Morvan. and the Centre de Biogénétique, Brest, France
,
Claude Ferec
1   From the Molecular Genetic Laboratory, CHU Morvan, Boulevard Tanguy Prigent, Brest, France
3   E.T.S.B.O., Brest, France
› Author Affiliations
Further Information

Publication History

Received 09 November 1998

Accepted after revision 05 January 1999

Publication Date:
09 December 2017 (online)

 

 
  • References

  • 1 Kierkegaard. Incidence of acute deep vein thrombosis in two districts. A phlebographic study. Acta Chir Scand 1980; 146: 267-9.
  • 2 Koster T, Rosendaal FR, Reitsma PH, van der Velden PA, Briët E, Vandenbroucke JP. Factor VII and fibrinogen levels as risk factors for venous thrombosis. Thromb Haemost 1994; 71: 719-22.
  • 3 Bertina RM, Koeleman BPC, Koster T. Mutation in blood coagulation factor V is associated with resistance to activated protein C. Nature 1994; 369: 64-7.
  • 4 Leroyer C, Mercier B, Escoffre M and al. Factor V Leiden prevalence in venous thromboembolism patients. Chest 1997; 111: 1603-6.
  • 5 Thomas A, Lamlun H, Humpries S, Green F. Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A-455 (Hae III), C/T-148 (Hind III/ Alu I), T/G+1689 (Ava II), and Bcl I (β fibrinogen) and Taq I (α fibrinogen), and their detection by PCR. Human Mutation 1994; 3: 79-81.