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Semin Thromb Hemost 2022; 48(07): 785-795
DOI: 10.1055/s-0042-1756192
Review Article

Role of Viscoelastic and Conventional Coagulation Tests for Management of Blood Product Replacement in the Bleeding Patient

Eduard Matkovic
1   Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
,
Paul F. Lindholm
1   Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
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Abstract

An important aim of viscoelastic testing (VET) is to implement transfusion algorithms based on coagulation test results to help reduce transfusion rates and improve patient outcomes. Establishing a rapid diagnosis and providing timely treatment of coagulopathy is the cornerstone of management of severely bleeding patients in trauma, postpartum hemorrhage, and major surgery. As the nature of acute bleeding and trauma leads to an unstable and tenuous physiologic state, conventional coagulation tests (CCTs) are too slow to diagnose, manage, and also course correct any hemostatic abnormalities that accompany an acute critical illness. Viscoelastic point-of-care tests strongly correlate with results from standard laboratory tests but are designed to enable clinicians to make timely, informed bleeding management decisions when time to intervene is critical. These assays provide an individualized and goal-oriented approach to patient blood management and are increasingly becoming involved in transfusion algorithms. The scope of this review aims to evaluate the current literature on VETs and their impact on actionable outputs in clinical decision making and their relationship to CCT.

Keywords

viscoelastic testing (VET) - blood transfusions - coagulopathy - conventional coagulation tests (CCTs)


Publikationsverlauf

Artikel online veröffentlicht:
29. September 2022

© 2022. Thieme. All rights reserved.

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