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Der Klinikarzt 2006; 35(5): 200-204
DOI: 10.1055/s-2006-947034
In diesem Monat

© Georg Thieme Verlag Stuttgart · New York

Mit Primärprävention bereits im Kindesalter beginnen - Risikofaktoren für eine Atherosklerose beim jungen Menschen

Primary Prevention Should Be Initiated Early in Life - Cardiovascular Risk Factors for Atherosclerosis in Children and Young AdultsE. Blessing1 , J. Tafel2 , J. Kreuzer3
  • 1Medizinische Klinik III, Universität Heidelberg (Ärztlicher Direktor: Prof. Dr. Katus)
  • 2Medizinische Klinik I, Universität Heidelberg (Ärztlicher Direktor: Prof. Dr. Nawroth)
  • 3Kardiologie, Medizinische Klinik, St. Vincenz Krankenhaus, Limburg an der Lahn (Chefarzt: Prof. Dr. J. Kreuzer)
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Publication History

Publication Date:
29 May 2006 (online)

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Atherosklerotische Veränderungen in der Aorta und den Koronararterien finden sich bereits im Kindes- und Jugendalter. Zahlreichen Autopsiestudien sowie nichtinvasiven Untersuchungen zufolge sind die bekannten kardiovaskulären Risikofaktoren bereits in jungen Jahren Ursache für die Entstehung früher atherosklerotischer Plaques und führen, vor allem bei Persistenz der Risikofaktoren, zur klinischen Manifestation von kardiovaskulären Erkrankungen im Erwachsenenalter. Eine Primärprävention oder Intervention bei Vorhandensein von Risikofaktoren ist daher essenziell und sollte bereits frühzeitig einsetzen.

Atherosclerotic changes in the aorta and coronary arteries can be found already early in childhood and adolescence. Numerous autopsy and non invasive studies clearly demonstrate, that the known cardiovascular risk factors play a causative role for the initiation of early atherosclerotic lesions. In case of persistence of risk factors, atherosclerosis often progresses and results in clinical manifestation of cardiovascular diseases in adulthood. Therefore, primary prevention or intervention in case of presence of cardiovascular risk factors is important and should be initiated early in life.

Key Words

atherosclerosis - early manifestation - risk factors - prevention

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1 Pathobiological Determinants of Atherosclerosis in Youth

2 Atherosclerosis Risk in Communities

3 Coronary Artery Risk Development in Young Adults

Anschrift für die Verfasser

PD Dr. Erwin Blessing

Medizinische Klinik III

Universität Heidelberg

Im Neuenheimer Feld 410

69120 Heidelberg

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