Pharmacopsychiatry 1989; 22(1): 34-37
DOI: 10.1055/s-2007-1014574
© Georg Thieme Verlag KG Stuttgart · New York

Predictors of Compliance with Lithium and Carbamazepine Regimens in the Long-Term Treatment of Recurrent Mood and Related Psychotic Disorders*

A.  Lenzi , F.  Lazzerini , G. F. Placidi , G. B. Cassano2 , H. S. Akiskal3
  • Institute of Clinical Psychiatry, University of Pisa, Italy
  • 2II Chair of Clinical Psychiatry, University of Pisa, Italy
  • 3Section of Affective Disorders, University of Tennessee, Memphis, U.S.A.
* This research was supported by a grant from the Italian Ministry of Public Education
Further Information

Publication History

Publication Date:
13 March 2008 (online)

Abstract

This study examined compliance with lithium and carbamazepine regimens from the perspective of the illness and its characteristics. Patients were more likely to stay in treatment when prophylaxis was begun following a depressive episode and in the presence of congruent psychotic experiences. The reverse was true for grandiose and manic patients and those with somatic preoccupations.

Riassunto

Questo studio esamina la compliance in pazienti con disturbi affettivi in terapia profilattica con sali di litio e carbamazepina. Ľinizio della profilassi immediatamente dopo un episodio depressivo e la presenza di manifestazioni psicotiche congrue con ľumore sono risultati essere predittori di buona compliance. AI contrario gli episodi maniacali e le preoccupazioni ipocondriache costituiscono indicatori di scarsa compliance.

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