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Horm Metab Res 1984; 16(12): 674-675
DOI: 10.1055/s-2007-1014881
DOI: 10.1055/s-2007-1014881
Short Communications
© Georg Thieme Verlag, Stuttgart · New York
Depressed Hypothalamic CRF Immunoreactivity in 15 Day Old Thiouracil-Treated Rats
Weitere Informationen
Publikationsverlauf
1984
1984
Publikationsdatum:
14. März 2008 (online)
Summary
Depression of thyroid status with thiouracil has been shown to delay the response of the hypothalamus-pituitaryadrenal axis to stress in young rats. In vivo and in vitro bioassay studies have indicated that the hypothalamus is the main site of axis alteration in 15 day old animals. The present study has found a significantly depressed hypothalamic content of immunoassayable corticotropin-releasing factor (CRF) in thiouracil treated young rats.
Key-Words:
Thiouracil - Corticotropin-Releasing Factor (CRF) - Radioimmunoassay (RIA)