ABSTRACT
Transit time flow volume has been used in cardiac surgery to assess small vessel flow
characteristics. This study examines the usefulness of transit time flow volume (TTFV)
in assessing perforator vessels in deep inferior epigastric artery perforator (DIEP)
flap harvesting. The purpose of this study was to evaluate the correlation among computed
tomographic angiography (CTA), intraoperative TTFV measurements, and hand-held Doppler
signals in identifying perforators. Ten consecutive free DIEP breast reconstructions
were prospectively evaluated using CTA to identify abdominal wall perforators. Intraoperatively,
perforating vessels >1 mm in diameter were evaluated with a conventional hand-held
8-MHz Doppler and a TTFV measurement device. Vessel location was correlated with preoperative
CTA . Waveform patterns and TTFV measurements were recorded for each vessel and correlated
with both CTA and hand-held Doppler signals. Of the 54 perforators identified, TTFV
showed arterial flow waveforms in 15 of 16 perforators identified by CTA and in 2
of the remaining 38 vessels. The sensitivity and specificity of TTFV in identifying
arterial perforators were 94 and 95%, respectively. In contradistinction, hand-held
Doppler was misleading in 70% of vessels. TTFV distinguishes arterial from venous
waveforms in vessels that appear arterial by hand-held Doppler signals. CTA and TTFV
are highly correlated, and the use of TTFV may prevent poor perfusion seen in some
DIEP flaps.
KEYWORDS
Transit time flow volume - computed tomography angiography - breast reconstruction
- DIEA perforator flap
REFERENCES
- 1
Rozen W M, Palmer K P, Suami H et al..
The DIEA branching pattern and its relationship to perforators: the importance of
preoperative computed tomographic angiography for DIEA perforator flaps.
Plast Reconstr Surg.
2008;
121
367-373
- 2
Rozen W M, Anavekar N S, Ashton M W et al..
Does the preoperative imaging of perforators with CT angiography improve operative
outcomes in breast reconstruction?.
Microsurgery.
2008;
28
516-523
- 3
Granzow J W, Levine J L, Chiu E S, Allen R J.
Breast reconstruction with the deep inferior epigastric perforator flap: history and
an update on current technique.
J Plast Reconstr Aesthet Surg.
2006;
59
571-579
- 4
Bonde C T, Christensen D E, Elberg J J.
Ten years' experience of free flaps for breast reconstruction in a Danish microsurgical
centre: an audit.
Scand J Plast Reconstr Surg Hand Surg.
2006;
40
8-12
- 5
Rozen W M, Phillips T J, Ashton M W, Stella D L, Gibson R N, Taylor G I.
Preoperative imaging for DIEA perforator flaps: a comparative study of computed tomographic
angiography and Doppler ultrasound.
Plast Reconstr Surg.
2008;
121
9-16
- 6
Rosson G D, Williams C G, Fishman E K, Singh N K.
3D CT angiography of abdominal wall vascular perforators to plan DIEAP flaps.
Microsurgery.
2007;
27
641-646
- 7
Tregaskiss A P, Goodwin A N, Bright L D, Ziegler C H, Acland R D.
Three-dimensional CT angiography: a new technique for imaging microvascular anatomy.
Clin Anat.
2007;
20
116-123
- 8
Tokuda Y, Song M H, Oshima H, Usui A, Ueda Y.
Predicting midterm coronary artery bypass graft failure by intraoperative transit
time flow measurement.
Ann Thorac Surg.
2008;
86
532-536
- 9
Desai N D, Miwa S, Kodama D et al..
A randomized comparison of intraoperative indocyanine green angiography and transit-time
flow measurement to detect technical errors in coronary bypass grafts.
J Thorac Cardiovasc Surg.
2006;
132
585-594
- 10
Groom R, Tryzelaar J, Forest R et al..
Intra-operative quality assessment of coronary artery bypass grafts.
Perfusion.
2001;
16
511-518
- 11
Beldi G, Bosshard A, Hess O M, Althaus U, Walpoth B H.
Transit time flow measurement: experimental validation and comparison of three different
systems.
Ann Thorac Surg.
2000;
70
212-217
- 12
D'Ancona G, Karamanoukian H L, Ricci M, Schmid S, Bergsland J, Salerno T A.
Graft revision after transit time flow measurement in off-pump coronary artery bypass
grafting.
Eur J Cardiothorac Surg.
2000;
17
287-293
- 13
Hirotani T, Kameda T, Shirota S, Nakao Y.
An evaluation of the intraoperative transit time measurements of coronary bypass flow.
Eur J Cardiothorac Surg.
2001;
19
848-852
- 14
Blondeel P N.
One hundred free DIEP flap breast reconstructions: a personal experience.
Br J Plast Surg.
1999;
52
104-111
- 15
Di Giammarco G, Pano M, Cirmeni S, Pelini P, Vitolla G, Di Mauro M.
Predictive value of intraoperative transit-time flow measurement for short-term graft
patency in coronary surgery.
J Thorac Cardiovasc Surg.
2006;
132
468-474
- 16
Kjaergard H K.
Baseline flow in coronary bypass grafts.
J Card Surg.
2005;
20
205-207
- 17
Lin C H, Chua C H, Chiang S S, Liou J Y, Hung H F, Chang C H.
Correlation of intraoperative blood flow measurement with autogenous arteriovenous
fistula outcome.
J Vasc Surg.
2008;
48
167-172
- 18
Imai R, Matsumura H, Tanaka K, Uchida R, Watanabe K.
Comparison of Doppler sonography and multidetector-row computed tomography in the
imaging findings of the deep inferior epigastric perforator artery.
Ann Plast Surg.
2008;
61
94-98
- 19
Sailon A M, Schachar J S, Levine J P.
Free transverse rectus abdominis myocutaneous and deep inferior epigastric perforator
flaps for breast reconstruction: a systematic review of flap complication rates and
donor-site morbidity.
Ann Plast Surg.
2009;
62
560-563
Claire TempleM.D.
Office Number: D0–217, 268 Grosvenor Street
London, Ontario, Canada N6A 4L6
eMail: ctemple4@uwo.ca