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Semin intervent Radiol 2014; 31(02): 129-137
DOI: 10.1055/s-0034-1373788
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Comparison of Percutaneous Ablation Technologies in the Treatment of Malignant Liver Tumors

Authors

  • Hyeon Yu

    1   Division of Vascular and Interventional Radiology, Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina

  • Charles T. Burke

    1   Division of Vascular and Interventional Radiology, Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina
Further Information

Publication History

Publication Date:
21 May 2014 (online)

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Abstract

Tumor ablation is a minimally invasive technique used to deliver chemical, thermal, electrical, or ultrasonic damage to a specific focal tumor in an attempt to achieve substantial tumor destruction or complete eradication. As the technology continues to advance, several image-guided tumor ablations have emerged to effectively manage primary and secondary malignancies in the liver. Percutaneous chemical ablation is one of the oldest and most established techniques for treating small hepatocellular carcinomas. However, this technique has been largely replaced by newer modalities including radiofrequency ablation, microwave ablation, laser-induced interstitial thermotherapy, cryoablation, high-intensity–focused ultrasound ablation, and irreversible electroporation. Because there exist significant differences in underlying technological bases, understanding each mechanism of action is essential for achieving desirable outcomes. In this article, the authors review the current state of each ablation method including technological and clinical considerations.

Keywords

percutaneous chemical ablation - radiofrequency ablation - irreversible electroporation - cryoablation - microwave ablation - high-intensity–focused ultrasound ablation - interventional radiology