Identification of Novel Polymorphisms within the Protein Z Gene, Haplotype Distribution and Linkage Analysis

• References

• 1 Ichinose A, Takeya H, Espling E, Iwanaga S, Kisiel W, Davie EW. Amino acid sequence of human Protein Z a vitamin K-dependent plasma glycoprotein. Biochem Biophys Res Commun 1990; 172: 1139-44.
• 2 Miletich JP, Broze GJJ. Human Plasma Protein Z Antigen: Range in Normal Subjects and Effect of Warfarin Therapy. Blood 1987; 69: 1580-6.
• 3 Han X, Fiehler R, Broze GJJ. Isolation of a protein Z-dependent plasma protease inhibitor. Proc Natl Acad Sci USA 1998; 95: 9250-5.
• 4 Yin Z-F, Huang Z-F, Cui J, Fiehler R, Lasky N, Ginsburg D, Broze GJJ. Prothrombotic phenotype of protein Z deficiency. Proc Natl Acad Sci USA 2000; 97: 6734-8.
• 5 Fujimaki K, Yamazaki T, Taniwaki M, Ichinose A. The Gene for Human Protein Z Is Localized to Chromosome 13 at Band q34 and Is Coded by Eight Regular Exons and One Alternative Exon. Biochemistry 1998; 37: 6838-46.
• 6 Liu W, Smith DI, Rechtzigel KJ, Thibodeau SN, James CD. Denaturing high performance liquid chromatography (DHPLC) used in the detection of germ-line and somatic mutations. Nucleic Acids Res 1998; 26: 1396-400.