Lipoxygenase Deficiency in Primary Thrombocythemia Is not a True Deficiency

Thromb Haemost 1994; 71(06): 803-804
DOI: 10.1055/s-0038-1642531

Letters to the Editor

Schattauer GmbH Stuttgart

Authors

Perry J J van Genderen

¹Department of Hematology, University Hospital Dijkzigt and Institute of Pharmacology, Erasmus University Medical School, Rotterdam, The Netherlands
Jan J Michiels

¹Department of Hematology, University Hospital Dijkzigt and Institute of Pharmacology, Erasmus University Medical School, Rotterdam, The Netherlands
Freek J Zijlstra

¹Department of Hematology, University Hospital Dijkzigt and Institute of Pharmacology, Erasmus University Medical School, Rotterdam, The Netherlands

References
1 Genderen PJJ van, Michiels JJ. Primary thrombocythemia: diagnosis, clinical manifestations and management. Ann Hematol 1993; 67: 57-62
2 Schafer AI. Deficiency of platelet lipoxygenase activity in myeloproliferative disorders. N Engl J Med 1982; 306: 381-6
3 Michiels JJ, Abels J, Steketee J, van Vliet HHDM, Vuzevski VD. Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. Ann Intern Med 1985; 102: 466-71
4 Barbui T, Buelli M, Cortelazzo S, Viero P, De Gaetano G. Aspirin and risk of bleeding in patients with thrombocythemia. Am J Med 1987; 83: 265-8