1.1. 2 Asymmetric Hydroformylation of Alkenes
Book
Editor: van Leeuwen, P. W. N. M.
Title: C-1 Building Blocks in Organic Synthesis 1
Subtitle: Additions to Alkenes, Alkynes, and Carbonyl Compounds
Print ISBN: 9783131707611; Online ISBN: 9783132064416; Book DOI: 10.1055/b-003-125818
2014 © 2014. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Subjects: C-1 Building Blocks in Organic Synthesis
Science of Synthesis Reference Libraries
Parent publication
Title: Science of Synthesis
DOI: 10.1055/b-00000101
Type: Multivolume Edition
Abstract
Asymmetric hydroformylation is a very promising catalytic reaction that produces chiral aldehydes from inexpensive feedstocks (alkenes and syngas) in a single step under essentially neutral reaction conditions. Asymmetric hydroformylation offers a great potential for the fine chemical industry since enantiomerically pure or enriched aldehydes can be obtained through hydroformylation of a variety of substrates using the appropriate chiral-phosphorus-modified rhodium catalyst. This chapter presents the successful transformations of benchmark and specific substrates, organized according to the substitution pattern.
Key words
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