2.6. 3 Kharasch Reaction (Atom-Transfer Radical Addition Reactions)
Buch
Herausgeber: van Leeuwen, P. W. N. M.
Titel: C-1 Building Blocks in Organic Synthesis 2
Untertitel: Alkenations, Cross Couplings, Insertions, Substitutions, and Halomethylations
Print ISBN: 9783131751218; Online ISBN: 9783132064515; Buch-DOI: 10.1055/b-003-125817
1st edition © 2014. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Fachgebiete: C1-bildende Blöcke in der organischen Synthese
Science of Synthesis Reference Libraries
Übergeordnete Publikation
Titel: Science of Synthesis
DOI: 10.1055/b-00000101
Typ: Mehrbändiges Werk
Abstract
Since the 1990s, highly active ruthenium and copper catalysts for atom-transfer radical addition (ATRA) reactions have been described and applications of these processes in organic synthesis have been developed. In this chapter are presented some examples of homologation reactions using carbon tetrahalide or haloform polyhalogenated compounds (halogen = Cl, Br) for atom-transfer radical addition for which isolated yields have been reported.
Schlüsselwörter
atom-transfer radical addition - Kharasch addition - transition-metal catalysis - one-carbon homologation - cyclization - polyhaloalkanes - alkenes - haloform - carbon tetrahalides-
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