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Faber, K. et al.: 2015 Science of Synthesis: Biocatalysis in Organic Synthesis DOI: 10.1055/sos-SD-216-00383
Biocatalysis in Organic Synthesis 3

3.10 Emerging Enzymes

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Book

Editors: Faber, K.; Fessner, W.-D.; Turner, N. J.

Authors: Allen, C. C. R.; de Gonzalo, G.; Ellinger, J. J.; Ewing, T. A.; Faber, K.; Fernández-Lucas, J.; Flynn, C. M.; Fraaije, M. W.; García-Junceda, E.; Garrabou, X.; Gkotsi, D. S.; Glueck, S. M.; Goss, R. J. M.; Grogan, G.; Gröger, H.; Grüschow, S.; Hammer, S. C.; Hauer, B.; Herter, S.; Hilvert, D.; Hollmann, F.; Hormigo, D.; Hummel, W.; Molla, G.; Nestl, B. M.; Nolte, J. C.; Obexer, R.; Oroz-Guinea, I.; Patel, R. N.; Pollegioni, L.; Quin, M. B.; Schmidt-Dannert, C.; Smith, D. R. M.; Turner, N. J.; Urlacher, V. B.; van Berkel, W. J. H.; Woodley, J. M.

Title: Biocatalysis in Organic Synthesis

Print ISBN: 9783131746610; Online ISBN: 9783131974914; Book DOI: 10.1055/b-003-125814

2015 © 2015. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry

Science of Synthesis Reference Libraries



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Type: Multivolume Edition

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Abstract

Nature has developed and adapted a large number of enzyme types. Remarkably, these enzymes may be further used in biocatalysis for synthetic purposes. This chapter provides an overview of emerging cases of novel enzymes. Herein, nitrile reductases, sulfatases, squalene hopene cyclases, and aldoxime dehydratases may provide very powerful novel synthetic approaches in the futures, as they catalyze chemically interesting reactions under very mild reaction conditions and with high selectivities. These biocatalysts comprise a broad field of options, whereby biocatalysis may contribute to the quest for novel chemistry for future applications.

Key words

emerging enzymes - nitrile reductase - inverting and retaining sulfatase - squalene hopene cyclase - aldoxime dehydratase
 
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