2.3 C—C Bond Formation Using Carbenes
Buch
Herausgeber: Yu, J.-Q.
Titel: Catalytic Transformations via C-H Activation 2
Print ISBN: 9783132057210; Online ISBN: 9783132404137; Buch-DOI: 10.1055/b-004-129675
1st edition © 2015 Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Fachgebiete: Organische Chemie
Science of Synthesis Reference Libraries
Übergeordnete Publikation
Titel: Science of Synthesis
DOI: 10.1055/b-00000101
Typ: Mehrbändiges Werk
Abstract
Transition-metal-catalyzed carbene C—H insertion has been developed as one of the most direct and effective methods for the construction of C—C bonds from C—H bonds. During the past two decades, a number of transition-metal-based catalytic systems have been established for asymmetric C—H functionalization via carbene insertion. Synthetically useful systems have been developed to functionalize C—H bonds in both intermolecular and intramolecular fashions. In this chapter, highly selective and practical catalytic systems for stereoselective C—H functionalization via catalytic carbene transfer are summarized. Literature reports are classified and discussed according to the type of C—H bond. This review focuses mainly on the issue of stereoselectivity, particularly on enantioselectivity.
Schlüsselwörter
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