Int J Angiol 1994; 3(1): 56-60
DOI: 10.1007/BF02014915
Original Articles

© Georg Thieme Verlag KG Stuttgart · New York

Progression of carotid atherosclerosis in Japanese patients with coronary artery disease

Kenji Sueyoshi1 , Hidekazu Tanaka2 , Kenji Mandai1 , Masami Nishino1 , Tasuo Itoh1 , Ryuzo Fukunaga1 , Yoshio Yamada1 , Hiroshi Abe1
  • 1Department of Internal Medicine, Osaka Rosai Hospital, Osaka, Japan
  • 2Department of Pharmacology 1, Osaka University School of Medicine, Osaka, Japan
Further Information

Publication History

Publication Date:
22 April 2011 (online)

Abstract

The authors investigated the relationship between the progression of carotid atherosclerosis and the severity of coronary artery disease (CAD). The two-year follow-ups of extracranial carotid atherosclerosis in 50 patients with CAD were evaluated by B-mode high-resolution ultrasonography. The summed maximal thickness of carotid plaques increased by 3.2 to 10.1 mm (mean 1.06 mm, SD 2.42 mm). The extent of coronary atherosclerosis (p < 0.02) and the serum total cholesterol level (p < 0.01) were different between the progressing group (n = 20) and the nonprogressing group (n = 25) with carotid atherosclerosis. Carotid disease progression was significantly higher in patients with three-vessel coronary disease than in those without significant coronary disease (p < 0.005). Age, serum triglyceride, high-density lipoprotein-cholesterol, pack-years of smoking, % smokers, % hypertensives, and % diabetics were not different between the two groups. It was concluded that the severity of CAD was one of the strong predictors for carotid disease progression in patients with CAD.

    >