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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2017; 04(02): 79-84
DOI: 10.1007/s40556-017-0115-5
Fetal Procedures

Chorionic Villus Sampling

Reema Kumar Bhatt
1   Department of Obstetrics and Gynecology, Army Hospital Research and Referral, 110010, New Delhi, India
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Abstract

Chorionic villus sampling (CVS) is a form of prenatal diagnosis to determine chromosomal or genetic disorders in the fetus. It entails sampling of the chorionic villus (placental tissue) and testing it for chromosomal abnormalities. It usually takes place at 10–12 weeks’ gestation, earlier than amniocentesis or percutaneous umbilical cord blood sampling. CVS was performed for the first time by Italian biologist Giuseppe Simoni. It requires expertise and is safe in the hands of experienced surgeons with a very low fetal loss rate.

Keywords

Chorionic villus sampling - Transcervical - Transabdominal - Complications - Oromandibular hypogenesis - Limb-reduction defects - Cytogenetics


Publication History

Received: 07 December 2016

Accepted: 30 January 2017

Article published online:
08 May 2023

© 2017. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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