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DOI: 10.1007/s40556-020-00248-5
Outcome of Aneurysmal Septum Primum with Non-restrictive Foramen Ovale in Fetuses with Structurally Normal Hearts: A Tertiary Center Experience

Abstract
The aim of this analysis was to study the postnatal short-term outcome of cases with aneurysmal septum primum (ASP) and non-restrictive foramen ovale in otherwise structurally normal hearts. This is a retrospective review of fetuses with ASP referred between 2016 and 2018 to the University Hospital of Cerrahpasa, Department of Fetal Cardiology for cardiac scanning. Prenatal and postnatal clinical features and outcomes for each case were ascertained from the departmental database and from individual clinical hospital records. We presented twenty-four cases which also had postnatal echocardiographic examination in our hospital. At the time of diagnosis of ASP, the mean maternal age was 31.1 ± 5.7 years, the mean gestational age was 28.9 ± 5.9 weeks, the mean birth week was 37.4 ± 3.1 weeks, and the mean birth weight was 2940.8 ± 736.6 g. The postnatal first 3 months prevalences of atrial septal aneurysm, patent foramen ovale and, secundum atrial septal defect (ASD) were 12.5%, 12.5%, 20.8% among fetuses with ASP, respectively. ASP may persist after birth and may increase the frequency of secundum ASD. These data suggest that fetuses with ASP should be followed by a pediatric cardiologist in postnatal life.
Keywords
Aneurysmal septum primum - Atrial septal aneurysm - Fetal echocardiography - Foramen ovale - Postnatal outcomePublication History
Received: 22 January 2020
Accepted: 27 February 2020
Article published online:
05 May 2023
© 2020. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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