Indian Journal of Neurotrauma 2012; 09(01): I-2
DOI: 10.1016/j.ijnt.2012.04.016
Editorial
Thieme Medical and Scientific Publishers Private Ltd.

Improving outcomes for patients with traumatic brain injury: The CRASH-3 trial in India

Haleema Shakur
a   Clinical Trials Unit, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK, Div. of Neurosurgery, Department of Neurosciences, FLT. Lt. Rajan Dhall Fortis Hospital, Vasant Kunj, Delhi NCR, New Delhi 110070, India   Email: ydewan@yahoo.com
,
Yashbir Dewan
a   Clinical Trials Unit, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK, Div. of Neurosurgery, Department of Neurosciences, FLT. Lt. Rajan Dhall Fortis Hospital, Vasant Kunj, Delhi NCR, New Delhi 110070, India   Email: ydewan@yahoo.com
› Author Affiliations

Subject Editor:
Further Information

Publication History

Publication Date:
05 April 2017 (online)

 
  • References

  • 1 Bruns J., Hauser W.. The epidemiology of traumatic brain injury: a review. Epilepsia 2003; 44 (Suppl. 10) 2-10
  • 2 Murray C., Lopez A.. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries and Risk Factors in 1990 and Projected to 2020. Harvard University Press; Cambridge, MA: 1996
  • 3 Peden M., Scurfield R., Sleet D.. et al World Report on Road Traffic Injury Prevention. World Health Organization; Geneva: 2004
  • 4 Gururaj G.. Road traffic deaths, injuries and disabilities in India: Current scenario. Natl Med J India 2008; 21: 14-20
  • 5 Henry D.A., Carless P.A., Moxey A.J.. et al Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2011; (03) CD001886
  • 6 The CRASH-2 Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. The Lancet 2010; 376 9734 23-32
  • 7 The CRASH-2 collaborators. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. The Lancet 2011; 377: 1096-1101
  • 8 Guerriero C., Cairns J., Perel P.. et al Cost-Effectiveness Analysis of Administering Tranexamic Acid to Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial. PLoS ONE 2011; 06 (05) e18987 doi: 10.1371/journal.pone.0018987
  • 9 CRASH-2 collaborators (Intracranial Bleeding Study). Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study). BMJ 2011; 343: d3795
  • 10 Yutthakasemsunt S, Kittiwattanagul W, Piyavechvirat P, Thinkhamrop B, Phuenpathom N; Lumbiganon P. Tranexamic Acid for preventing progressive intracranial hemorrage in adults with traumatic brain injury; a preliminary report presented at the National Neurotrauma Symposium 2010. Available from http://www.neurotrauma.org/2010/abstracts.htm .