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CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2019; 54(01): 033-036
DOI: 10.1016/j.rbo.2017.09.006
Original Article | Artigo Original
Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revnter Publicações Ltda Rio de Janeiro, Brazil

Biopsy Path Contamination in Primary Bone Sarcomas[*]

Article in several languages: português | English
Jairo Greco Garcia
1   Setor de Ortopedia Oncológica da Disciplina de Ortopedia, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
,
Dayane Screpante Marques
2   Escola Paulista de Medicina, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
,
Dan Carai Maia Viola
1   Setor de Ortopedia Oncológica da Disciplina de Ortopedia, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
,
Marcelo de Toledo Petrilli
1   Setor de Ortopedia Oncológica da Disciplina de Ortopedia, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
,
Maria Teresa de Seixas Alves
3   Disciplina de Anatomia Patológica, Geral, Sistêmica Forense e Bioética, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
,
Reynaldo Jesus-Garcia Filho
1   Setor de Ortopedia Oncológica da Disciplina de Ortopedia, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
› Author Affiliations
Further Information

Publication History

11 August 2017

05 September 2017

Publication Date:
01 March 2019 (online)

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Abstract

Objective

To determine the incidence of contamination of the biopsy pathway in patients with primary bone sarcomas, as well as the clinical characteristics that influenced this outcome.

Materials and Methods

The anatomopathological reports of the patients who were treated by the Orthopedic Oncology Sector of the Orthopedic and Traumatology Department of this institution were retrospectively evaluated.

Results

Of the 148 patients included for evaluation in the present study, only 1 presented contamination by neoplastic cells in his biopsy pathway.

Conclusion

The bone biopsy procedure in patients with primary bone sarcomas presents great safety regarding pathway contamination when performed in specialized centers that treat this type of pathology.

Keywords

Ewing sarcoma - osteosarcoma - biopsy

* Work developed at the Departament of Ortopedics and Traumatology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.


 

  • Referências

  • 1 Valls J, Ottolenghi CE, Schajowicz F. La biopsia por aspiracion en el disgnostico de las lesiones oseas. Buenos Aires: El Ateneo; 1942
    Google Scholar
  • 2 Barbosa Ribeiro M, Oliveira CRG, Filippi RZ, Baptista AM, Caiero MT, Saito CF. , et al. Estudo histopatológico do trajeto de biópsia de tumores musculoesqueléticos malignos. Acta Ortop Bras 2009; 17 (05) 279-81
    CrossrefGoogle Scholar
  • 3 Mankin HJ, Mankin CJ, Simon MA. ; Members of the Musculoskeletal Tumor Society. The hazards of the biopsy, revisited. J Bone Joint Surg Am 1996; 78 (05) 656-63
    CrossrefPubMedGoogle Scholar
  • 4 Mavrogenis AF, Coll-Mesa L, Gonzalez-Gaitan M, Ucelay-Gomez R, Fabri N, Ruggieri P. , et al. Criteria and outcome of limb salvage surgery. J BUON 2011; 16 (04) 617-26
    PubMedGoogle Scholar
  • 5 Campanacci M. Bone and soft tissue tumors. New York: Springer Verlag; 1990
    Google Scholar
  • 6 Traina F, Errani C, Toscano A, Pungetti C, Fabbri D, Mazzotti A. , et al. Current concepts in the biopsy of musculoskeletal tumors: AAOS exhibit selection. J Bone Joint Surg Am 2015; 97 (02) e7
    CrossrefPubMedGoogle Scholar
  • 7 Moore TM, Meyers MH, Patzakis MJ, Terry R, Harvey Jr JP. Closed biopsy of musculoskeletal lesions. J Bone Joint Surg Am 1979; 61 (03) 375-80
    CrossrefPubMedGoogle Scholar
  • 8 Simon MA, Biermann JS. Biopsy of bone and soft-tissue lesions. J Bone Joint Surg Am 1993; 75 (04) 616-21
    CrossrefPubMedGoogle Scholar
  • 9 Li ZF, Li JM, Yan J, Yang ZP, Li X, Yang Q. Prevention of contamination by biopsy needle track contamination using a novel adriamycin-loaded gelatin sponge. World J Surg Oncol 2013; 11: 169
    CrossrefPubMedGoogle Scholar
  • 10 Oliveira MP, Lima PM, da Silva HJ, de Mello RJ. Neoplasm seeding in biopsy tract of the musculoskeletal system. A systematic review. Acta Ortop Bras 2014; 22 (02) 106-10
    CrossrefPubMedGoogle Scholar
  • 11 Enneking WF. A system of staging musculoskeletal neoplasms. Clin Orthop Relat Res 1986; (204) 9-24
    PubMedGoogle Scholar
  • 12 Huvos AG, Rosen G, Marcove RC. Primary osteogenic sarcoma: pathologic aspects in 20 patients after treatment with chemotherapy en bloc resection, and prosthetic bone replacement. Arch Pathol Lab Med 1977; 101 (01) 14-8
    PubMedGoogle Scholar
  • 13 Mohana R, Faisham W, Zulmi W, Nawfar AS, Effat O, Salzihan MS. The incidence of malignant infiltration in the biopsy tract of osteosarcoma. Malays Orthop J 2007; 1 (02) 7-10
    CrossrefGoogle Scholar
  • 14 Cannon SR, Dyson PHP. Relationship of the site of open biopsy of malignant bone tumors to local recurrence following resection and prosthetic replacement. J Bone Joint Surg Br 1987; 69: 492
    Google Scholar
  • 15 Kaffenberger BH, Wakely Jr PE, Mayerson JL. Local recurrence rate of fine-needle aspiration biopsy in primary high-grade sarcomas. J Surg Oncol 2010; 101 (07) 618-21
    CrossrefPubMedGoogle Scholar
  • 16 Saghieh S, Masrouha KZ, Musallam KM, Mahfouz R, Abboud M, Khoury NJ. , et al. The risk of local recurrence along the core-needle biopsy tract in patients with bone sarcomas. Iowa Orthop J 2010; 30: 80-3
    PubMedGoogle Scholar