Handchir Mikrochir Plast Chir 2018; 50(05): 335-340
DOI: 10.1055/a-0747-5982
Originalarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Risk Factors of Carpal Tunnel Syndrome for Male Patient Undergoing Carpal Tunnel Release

Risikofaktoren für Karpaltunnelsyndrom bei männlichen Patienten
Jun-Ku Lee
1   Inje University Seoul Paik Hospital Department of Orthopaedic Surgery
,
Soo-Hyun Lee
2   Bundang CHA Medical Center Department of Orthopedic surgery
,
Banghyun Kim
3   Saenarae Hospital Department of Orthopaedic Surgery
,
Kyunghun Jung
2   Bundang CHA Medical Center Department of Orthopedic surgery
,
Inkeun Park
1   Inje University Seoul Paik Hospital Department of Orthopaedic Surgery
,
Soo-Hong Han
2   Bundang CHA Medical Center Department of Orthopedic surgery
› Author Affiliations
Further Information

Publication History

04/08/2018

09/14/2018

Publication Date:
07 November 2018 (online)

Abstract

Introduction Although the major cause of carpal tunnel syndrome (CTS) remains idiopathic, many male CTS patients are clinically different from female patients and often have specific risk factors associated with their conditions. An accurate analysis of such propensity has yet to be established. The purpose of this study is to compare male and female patients by analyzing the risk factors associated with CTS patients who underwent surgical treatment, with focus on their occupation.

Patients/Material and Methods retrospective chart review of 818 patients with CTS was performed to identify the associated risk factors. Patients were stratified by gender: female (n = 707, 86.4 %) and male (n = 111, 13.6 %). The mean patient age was 54.5 (range: 16–85 yr.) for all groups. The medical history and risk factors of each patient was thoroughly reviewed by medical charts and telephone survey. We categorized the risk factors of CTS into 7 categories: anatomic, neuropathic, inflammatory, alteration of fluid balance, distal radius fracture associated, occupational risk factor related, and idiopathic. Occupations of CTS patients were divided into high risk occupations (vibratory tools, assembly jobs, and food processing and packaging jobs, and other occupations of repetitive wrist motion and forceful gripping) and nonrisk occupations. All variables were analyzed with chi-square or Fisher’s exact test for differences between men and women.

Results The number of individuals with known risk factors of CTS was greater in male, compared to that of female patients; 97 (87.4 %) male patients had the risk factors of CTS, while 361 (51.1 %) female patients (p < 0.001) did. In subgroup analysis of risk factors, male patients had frequent risk factors in neuropathic, inflammatory, and alteration of fluid balance (p < 0.001). Occupational risk was strongly associated with male gender (p < 0.001).

Conclusion Male CTS patients who underwent surgery are more likely to have a reason and have many occupational risk factors than women.

Zusammenfassung

Hintergrund Auch wenn die Mehrzahl an Karpaltunnelsyndromen (KTS) idiopathischer Natur ist, so gibt es doch Risikofaktoren für die Entwicklung eines KTS. Dabei ist allein schon aufgrund der unterschiedlichen Prävalenz des KTS bei Männern und Frauen von unterschiedlichen geschlechtsspezifischen Risikofaktoren auszugehen. Solche wurden bis dato nicht untersucht. Ziel dieser Studie war es entsprechend bei Patienten mit Z.n. KT-Dekompression unter besonderer Berücksichtigung der beruflichen Tätigkeit geschlechtsspezifische Risikofaktoren für die Entwicklung eines KTS zu ermitteln.

Patienten/Material und Methoden Die Akten von 818 Patienten mit Z.n. Karpaltunneloperation wurden unter Berücksichtigung des Geschlechts der Patienten (707 Frauen = 86,4 % und 111 Männer = 13,6 %) bzgl. möglicher Risikofaktoren für die Entstehung eines KTS retrospektiv ausgewertet. Zusätzlich erfolgten telefonische Befragungen. Das mittlere Alter aller Patienten betrug 54,5 (16–85) Jahre. Risikofaktoren für die Entstehung eines KTS wurden in 7 Gruppen unterteilt: anatomisch, neuropathisch, inflammatorisch, Dysbalance des Körpergewichts/flüßigkeit, Zusammenhang mit einem Bruch des distalen Radius, berufliches Risiko und idiopathisch. Es wurde unterschieden zwischen Berufen mit hohem und niedrigem Risiko zur Entwicklung eines KTS. Als Berufe mit hohem Risiko wurden eingestuft: Arbeiten mit vibrierenden Werkzeugen, Montagetätigkeit, Lebensmittelverpackung und Verarbeitung sowie Berufe mit repetitiven Bewegungen des Handgelenks und solche, die ein festes Zugreifen erfordern. Alle Variablen wurden statistisch auf Unterschiede zwischen Männern und Frauen analysiert.

Ergebnisse: Bei Männern (97 = 87,4%) ließen sich häufiger Risikofaktoren für die Entstehung eines KTS identifizieren als bei Frauen (351 = 51,1%) (p < 0,001). Im Vordergrund standen dabei neuropathische und inflamatorische Faktoren sowie Übergewicht (p < 0,001). Insbesondere Männer wiesen berufliche Risiken für ein KTS auf (p < 0,001).

Schlussfolgerung: Bei Männern mit Z.n. KT-Operation lässt sich häufiger eine Ursache für die Entstehung des KTS identifizieren als bei Frauen, wobei dem Beruf ein große Bedeutung zu kommt.

 
  • References

  • 1 Atroshi I, Gummesson C, Johnsson R. et al. Prevalence of carpal tunnel syndrome in a general population. Jama 1999; 282: 153-158
  • 2 von Schroeder HP, Botte MJ. Carpal tunnel syndrome. Hand Clin 1996; 12: 643-655
  • 3 Foley M, Silverstein B, Polissar N. The economic burden of carpal tunnel syndrome: long-term earnings of CTS claimants in Washington State. American journal of industrial medicine 2007; 50: 155-172
  • 4 Blanc PD, Faucett J, Kennedy JJ. et al. Self-reported carpal tunnel syndrome: predictors of work disability from the National Health Interview Survey Occupational Health Supplement. American journal of industrial medicine 1996; 30: 362-368
  • 5 Daniell WE, Fulton-Kehoe D, Chiou LA. et al. Work-related carpal tunnel syndrome in Washington State workers’ compensation: temporal trends, clinical practices, and disability. American journal of industrial medicine 2005; 48: 259-269
  • 6 Leigh JP, Miller TR. Occupational illnesses within two national data sets. International journal of occupational and environmental health 1998; 4: 99-113
  • 7 Becker J, Nora DB, Gomes I. et al. An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2002; 113: 1429-1434
  • 8 Boz C, Ozmenoglu M, Altunayoglu V. et al. Individual risk factors for carpal tunnel syndrome: an evaluation of body mass index, wrist index and hand anthropometric measurements. Clinical neurology and neurosurgery 2004; 106: 294-299
  • 9 Geoghegan JM, Clark DI, Bainbridge LC. et al. Risk factors in carpal tunnel syndrome. Journal of hand surgery (Edinburgh, Scotland) 2004; 29: 315-320
  • 10 de Krom MC, Kester AD, Knipschild PG. et al. Risk factors for carpal tunnel syndrome. American journal of epidemiology 1990; 132: 1102-1110
  • 11 Solomon DH, Katz JN, Bohn R. et al. Nonoccupational risk factors for carpal tunnel syndrome. Journal of general internal medicine 1999; 14: 310-314
  • 12 Spahn G, Wollny J, Hartmann B. et al. [Metaanalysis for the evaluation of risk factors for carpal tunnel syndrome (CTS) Part I. General factors]. Zeitschrift fur Orthopadie und Unfallchirurgie 2012; 150: 503-515
  • 13 Spahn G, Wollny J, Hartmann B. et al. [Metaanalysis for the evaluation of risk factors for carpal tunnel syndrome (CTS) Part II. Occupational risk factors]. Zeitschrift fur Orthopadie und Unfallchirurgie 2012; 150: 516-524
  • 14 Karpitskaya Y, Novak CB, Mackinnon SE. Prevalence of smoking, obesity, diabetes mellitus, and thyroid disease in patients with carpal tunnel syndrome. Annals of plastic surgery 2002; 48: 269-273
  • 15 Bicknell JM, Lim AC, Raroque Jr HG. et al. Carpal tunnel syndrome, subclinical median mononeuropathy, and peripheral polyneuropathy: common early complications of chronic peritoneal dialysis and hemodialysis. Archives of physical medicine and rehabilitation 1991; 72: 378-381
  • 16 de Krom MC, Knipschild PG, Kester AD. et al. Carpal tunnel syndrome: prevalence in the general population. Journal of clinical epidemiology 1992; 45: 373-376
  • 17 Shiri R, Pourmemari MH, Falah-Hassani K. et al. The effect of excess body mass on the risk of carpal tunnel syndrome: a meta-analysis of 58 studies. Obes Rev 2015; 16: 1094-1104
  • 18 Hakim AJ, Cherkas L, El Zayat S. et al. The genetic contribution to carpal tunnel syndrome in women: a twin study. Arthritis Rheum 2002; 47: 275-279
  • 19 Nishihori T, Choi J, DiGiovanna MP. et al. Carpal tunnel syndrome associated with the use of aromatase inhibitors in breast cancer. Clinical breast cancer 2008; 8: 362-365
  • 20 Bernard BP, Putz-Anderson V. Musculoskeletal disorders and workplace factors; a critical review of epidemiologic evidence for work-related musculoskeletal disorders of the neck, upper extremity, and low back. DOI:
  • 21 Uchiyama S, Itsubo T, Nakamura K. et al. Current concepts of carpal tunnel syndrome: pathophysiology, treatment, and evaluation. J Orthop Sci 2010; 15: 1-13
  • 22 Confino-Cohen R, Lishner M, Savin H. et al. Response of carpal tunnel syndrome to hormone replacement therapy. BMJ (Clinical research ed) 1991; 303: 1514
  • 23 Sternbach G. The carpal tunnel syndrome. The Journal of emergency medicine 1999; 17: 519-523
  • 24 Goda A, Masuyama T. Obesity and Overweight in Asian People. Circulation journal : official journal of the Japanese Circulation Society 2016; 80: 2425-2426
  • 25 Takahashi T, Lapham G, Chavez LJ. et al. Comparison of DSM-IV and DSM-5 criteria for alcohol use disorders in VA primary care patients with frequent heavy drinking enrolled in a trial. Addiction science & clinical practice 2017; 12: 17
  • 26 Palmer KT. Carpal tunnel syndrome: the role of occupational factors. Best practice & research Clinical rheumatology 2011; 25: 15-29
  • 27 Kerwin G, Williams CS, Seiler 3 rd JG. The pathophysiology of carpal tunnel syndrome. Hand Clin 1996; 12: 243-251
  • 28 Pope D, Tang P. Carpal Tunnel Syndrome and Distal Radius Fractures. Hand Clin 2018; 34: 27-32
  • 29 Hagberg M, Morgenstern H, Kelsh M. Impact of occupations and job tasks on the prevalence of carpal tunnel syndrome. Scandinavian journal of work, environment & health 1992; 18: 337-345
  • 30 Dale AM, Harris-Adamson C, Rempel D. et al. Prevalence and incidence of carpal tunnel syndrome in US working populations: pooled analysis of six prospective studies. Scandinavian journal of work, environment & health 2013; 39: 495-505
  • 31 Szabo RM, Madison M. Carpal tunnel syndrome. Orthop Clin North Am 1992; 23: 103-109
  • 32 Newington L, Harris EC, Walker-Bone K. Carpal tunnel syndrome and work. Best practice & research Clinical rheumatology 2015; 29: 440-453
  • 33 Michelsen H, Posner MA. Medical history of carpal tunnel syndrome. Hand Clin 2002; 18: 257-268
  • 34 Nordstrom DL, Vierkant RA, Layde PM. et al. Comparison of self-reported and expert-observed physical activities at work in a general population. American journal of industrial medicine 1998; 34: 29-35