Zirkulierende und disseminierte Tumorzellen beim Mammakarzinom

Zusammenfassung

Hämatogene Dissemination von Tumorzellen bei Mammakarzinom gehört zu den am intensivsten erforschten Gebieten der translationalen Onkologie. Große Metaanalysen haben die prognostische Relevanz der disseminierten Tumorzellen im Knochenmark und der zirkulierenden Tumorzellen im peripheren Blut sowohl in der Adjuvanz als auch im metastasierten Setting gezeigt. Im Rahmen der Jahrestagung der Deutschen Gesellschaft für Senologie in Berlin wurde der aktuelle Stand der Forschung intensiv diskutiert. Der folgende Kongressbericht gibt einen Überblick über die klinische Studienlandschaft und die neuen methodischen Entwicklungen zur Verbesserung der Detektion und der Phänotypisierung der zirkulierenden und disseminierten Tumorzellen.

Schlüsselwörter

Tumorzelldissemination - zirkulierende Tumorzellen - disseminierte Tumorzellen - Mammakarzinom

• References/Literatur

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