Gastric Emptying of Low- and High-Caloric Liquid Meals Measured Using Ultrasonography in Healthy Volunteers

Tarek Mazzawi; Emily Bartsch; Sara Benammi; Rosa Maria Carrasco Ferro; Ekaterina Nikitina; Nancy Nimer; Lara Jiménez Ortega; Charles Perrotte; Joäo Vitor Pithon; Safira Rosalina; Alexis Sharp; Reza Stevano; Jan Gunnar Hatlebakk; Trygve Hausken

doi:10.1055/a-0783-2170

Ultrasound International Open, Table of Contents

CC BY-NC-ND 4.0 · Ultrasound Int Open 2019; 05(01): E27-E33
DOI: 10.1055/a-0783-2170

Original Article

Gastric Emptying of Low- and High-Caloric Liquid Meals Measured Using Ultrasonography in Healthy Volunteers

Authors

Tarek Mazzawi

¹Department of Medicine, Haukeland University Hospital, Bergen, Norway

²Clinical Medicine, University of Bergen, Bergen, Norway
Emily Bartsch

²Clinical Medicine, University of Bergen, Bergen, Norway
Sara Benammi

²Clinical Medicine, University of Bergen, Bergen, Norway
Rosa Maria Carrasco Ferro

²Clinical Medicine, University of Bergen, Bergen, Norway
Ekaterina Nikitina

²Clinical Medicine, University of Bergen, Bergen, Norway
Nancy Nimer

²Clinical Medicine, University of Bergen, Bergen, Norway
Lara Jiménez Ortega

²Clinical Medicine, University of Bergen, Bergen, Norway
Charles Perrotte

²Clinical Medicine, University of Bergen, Bergen, Norway
Joäo Vitor Pithon

²Clinical Medicine, University of Bergen, Bergen, Norway
Safira Rosalina

²Clinical Medicine, University of Bergen, Bergen, Norway
Alexis Sharp

²Clinical Medicine, University of Bergen, Bergen, Norway
Reza Stevano

²Clinical Medicine, University of Bergen, Bergen, Norway
Jan Gunnar Hatlebakk

¹Department of Medicine, Haukeland University Hospital, Bergen, Norway

²Clinical Medicine, University of Bergen, Bergen, Norway
Trygve Hausken

¹Department of Medicine, Haukeland University Hospital, Bergen, Norway

²Clinical Medicine, University of Bergen, Bergen, Norway

Abstract

Purpose

Delayed gastric emptying is present in patients with functional dyspepsia (FD), diabetes mellitus, and neurological diseases. Diet may affect gastric emptying symptoms in patients with FD. We sought to determine the extent to which gastric emptying and symptoms of dyspepsia are influenced by caloric content in healthy subjects using ultrasonography.

Materials and Methods

32 healthy volunteers were given 2 meals with different caloric content in random order. Gastric emptying was determined using ultrasonography to measure antral area when fasting, and postprandially at intervals of 0, 10, 20, and 30 min. Dyspeptic symptoms including discomfort, nausea, and fullness were graded.

Results

The antral area following a high-caloric meal compared to a low-caloric meal was significantly increased at 0, 10, 20, and 30 min (P=0.0203,<0.0001<0.0001,<0.0001, respectively), as was the median fullness (P<0.0048, 0.0001, 0.0009, 0.0001, respectively) measured at the same time points. There was a weak correlation (r2=0.1, P<0.0001) between the antral area and subjective fullness. No differences between gastric emptying in males and females were found.

Conclusion

The caloric content of a meal influences gastric emptying. Using ultrasonography to measure the antral area helps us to assess gastric emptying and therefore to assess patients with functional dyspepsia.

Key words

antral area - caloric meal - functional dyspepsia - gastric emptying - ultrasonography

Full Text

References

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