Int J Sports Med 2019; 40(11): 683-695
DOI: 10.1055/a-0902-8539
Review
© Georg Thieme Verlag KG Stuttgart · New York

Radiographic Osteoarthritis Prevalence Over Ten Years After Anterior Cruciate Ligament Reconstruction

Tianwu Chen
1   Sports Medicine Department, Huashan Hospital Fudan University, Shanghai, China
,
Shuang Wang
2   Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
,
Yunxia Li
1   Sports Medicine Department, Huashan Hospital Fudan University, Shanghai, China
,
Chengchong Ai
1   Sports Medicine Department, Huashan Hospital Fudan University, Shanghai, China
,
Fangyi Jiang
1   Sports Medicine Department, Huashan Hospital Fudan University, Shanghai, China
,
Shiyi Chen
1   Sports Medicine Department, Huashan Hospital Fudan University, Shanghai, China
› Author Affiliations
Further Information

Publication History



accepted 09 April 2019

Publication Date:
12 August 2019 (online)

Abstract

The purpose of this study was to conduct an up-to-date systematic review and meta-analysis of radiographic knee osteoarthritis (OA) over minimal ten years after ACL reconstruction. The database of Pubmed and the Ovid was adopted. The radiographic knee OA over minimal ten years after ACL reconstruction was systematically reviewed. Both the ipsilateral and contralateral knees were evaluated referring to the tibiofemoral joint (TFJ), the patellofemoral joint (PFJ), and the overall knee OA prevalence. Nineteen studies were included for review, with nine screened for the meta-analysis. The overall knee OA rate ranged from 8.3–79.2%, meanly 51.6% on the ipsilateral side; ranged from 3.6–35.7%, meanly 15.5% on the contralateral side. Compared to the contralateral side, the RR of developing radiographic OA was 3.73 (P<0.01) for the overall knee, 2.88 (P<0.01) for TFJ, and 2.42 (P<0.01) for PFJ. Ipsilaterally, the RR of developing TFJ radiographic OA was 1.15 (P<0.01) compared to that of the PFJ. Over a minimum of 10 years after surgery, more than half the cases developed overall radiographic OA on the ipsilateral knee, which was nearly four times higher than the contralateral side. On the ipsilateral knee, the TFJ was most affected.

 
  • References

  • 1 Bjornsson H, Samuelsson K, Sundemo D, Desai N, Sernert N, Rostgard-Christensen L, Karlsson J, Kartus J. A randomized controlled trial with mean 16-year follow-up comparing hamstring and patellar tendon autografts in anterior cruciate ligament reconstruction. Am J Sports Med 2016; 44: 2304-2313
  • 2 Cohen M, Amaro JT, Ejnisman B, Carvalho RT, Nakano KK, Peccin MS, Teixeira R, Laurino CFS, Abdalla RJ. Anterior cruciate ligament reconstruction after 10–15 years: association between meniscectomy and osteoarthrosis. Arthroscopy 2007; 23: 629-634
  • 3 Crawford SN, Waterman BR, Lubowitz JH. Long-term failure of anterior cruciate ligament reconstruction. Arthroscopy 2013; 29: 1566-1571
  • 4 Gerhard P, Bolt R, Duck K, Mayer R, Friederich NF, Hirschmann MT. Long-term results of arthroscopically assisted anatomical single-bundle anterior cruciate ligament reconstruction using patellar tendon autograft: Are there any predictors for the development of osteoarthritis?. Knee Surg Sports Traumatol Arthrosc 2013; 21: 957-964
  • 5 Hoffelner T, Resch H, Moroder P, Atzwanger J, Wiplinger M, Hitzl W, Tauber M. No increased occurrence of osteoarthritis after anterior cruciate ligament reconstruction after isolated anterior cruciate ligament injury in athletes. Arthroscopy 2012; 28: 517-525
  • 6 Leiter JR, Gourlay R, McRae S, de Korompay N, MacDonald PB. Long-term follow-up of ACL reconstruction with hamstring autograft. Knee Surg Sports Traumatol Arthrosc 2014; 22: 1061-1069
  • 7 Mansson O, Sernert N, Rostgard-Christensen L, Kartus J. Long-term clinical and radiographic results after delayed anterior cruciate ligament reconstruction in adolescents. Am J Sports Med 2015; 43: 138-145
  • 8 Meuffels DE, Favejee MM, Vissers MM, Heijboer MP, Reijman M, Verhaar JA. Ten year follow-up study comparing conservative versus operative treatment of anterior cruciate ligament ruptures. A matched-pair analysis of high level athletes. Br J Sports Med 2009; 43: 347-351
  • 9 Myklebust G, Holm I, Maehlum S, Engebretsen L, Bahr R. Clinical, functional, and radiologic outcome in team handball players 6–11 years after anterior cruciate ligament injury: A follow-up study. Am J Sports Med 2003; 31: 981-989
  • 10 Peck J. Long-term sequelae and management following anterior cruciate ligament injury. BMJ Case Rep 2014; 2014: bcr2014204239
  • 11 Sanders TL, Pareek A, Kremers HM, Bryan AJ, Levy BA, Stuart MJ, Dahm DL, Krych AJ. Long-term follow-up of isolated ACL tears treated without ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2017; 25: 493-500
  • 12 Spindler KP, Parker RD, Andrish JT, Kaeding CC, Wright RW, Marx RG, McCarty EC, Amendola A, Dunn WR, Huston LJ, Harrell FE Jr. MOON Group.. Prognosis and predictors of ACL reconstructions using the MOON cohort: a model for comparative effectiveness studies. J Orthop Res 2013; 31: 2-9
  • 13 Lohmander LS, Englund PM, Dahl LL, Roos EM. The long-term consequence of anterior cruciate ligament and meniscus injuries: Osteoarthritis. Am J Sports Med 2007; 35: 1756-1769
  • 14 Pinczewski LA, Lyman J, Salmon LJ, Russell VJ, Roe J, Linklater J. A 10-year comparison of anterior cruciate ligament reconstructions with hamstring tendon and patellar tendon autograft: A controlled, prospective trial. Am J Sports Med 2007; 35: 564-574
  • 15 Risberg MA, Holm I, Steen H, Eriksson J, Ekeland A. The effect of knee bracing after anterior cruciate ligament reconstruction. A prospective, randomized study with two years' follow-up. Am J Sports Med 1999; 27: 76-83
  • 16 Struewer J, Frangen TM, Ishaque B, Bliemel C, Efe T, Ruchholtz S, Ziring E. Knee function and prevalence of osteoarthritis after isolated anterior cruciate ligament reconstruction using bone-patellar tendon-bone graft: Long-term follow-up. Int Orthop 2012; 36: 171-177
  • 17 Falciglia F, Panni AS, Giordano M, Aulisa AG, Guzzanti V. Anterior cruciate ligament reconstruction in adolescents (Tanner stages 2 and 3). Knee Surg Sports Traumatol Arthrosc 2016; 24: 807-814
  • 18 Gillquist J, Messner K. Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med 1999; 27: 143-156
  • 19 Oiestad BE, Engebretsen L, Storheim K, Risberg MA. Knee osteoarthritis after anterior cruciate ligament injury: A systematic review. Am J Sports Med 2009; 37: 1434-1443
  • 20 Claes S, Hermie L, Verdonk R, Bellemans J, Verdonk P. Is osteoarthritis an inevitable consequence of anterior cruciate ligament reconstruction? A meta-analysis. Knee Surg Sports Traumatol Arthrosc 2013; 21: 1967-1976
  • 21 Ajuied A, Wong F, Smith C, Norris M, Earnshaw P, Back D, Davies A. Anterior cruciate ligament injury and radiologic progression of knee osteoarthritis: A systematic review and meta-analysis. Am J Sports Med 2014; 42: 2242-2252
  • 22 Barenius B, Ponzer S, Shalabi A, Bujak R, Norlen L, Eriksson K. Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: A 14-year follow-up study of a randomized controlled trial. Am J Sports Med 2014; 42: 1049-1057
  • 23 Bjorkman P, Sandelin J, Harilainen A. A randomized prospective controlled study with 5-year follow-up of cross-pin femoral fixation versus metal interference screw fixation in anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2015; 23: 2353-2359
  • 24 Culvenor AG, Collins NJ, Guermazi A, Cook JL, Vicenzino B, Whitehead TS, Morris HG, Crossley KM. Early patellofemoral osteoarthritis features one year after anterior cruciate ligament reconstruction: Symptoms and quality of life at three years. Arthritis Care Res (Hoboken) 2016; 68: 784-792
  • 25 Culvenor AG, Lai CC, Gabbe BJ, Makdissi M, Collins NJ, Vicenzino B, Morris HG, Crossley KM. Patellofemoral osteoarthritis is prevalent and associated with worse symptoms and function after hamstring tendon autograft ACL reconstruction. Br J Sports Med 2014; 48: 435-439
  • 26 Culvenor AG, Oiestad BE, Holm I, Gunderson RB, Crossley KM, Risberg MA. Anterior knee pain following anterior cruciate ligament reconstruction does not increase the risk of patellofemoral osteoarthritis at 15- and 20-year follow-ups. Osteoarthritis Cartilage 2017; 25: 30-33
  • 27 Ferretti A, Monaco E, Ponzo A, Basiglini L, Iorio R, Caperna L, Conteduca F. Combined intra-articular and extra-articular reconstruction in anterior cruciate ligament-deficient knee: 25 years later. Arthroscopy 2016; 32: 2039-2047
  • 28 Peterson L, Eklund U, Engstrom B, Forssblad M, Saartok T, Valentin A. Long-term results of a randomized study on anterior cruciate ligament reconstruction with or without a synthetic degradable augmentation device to support the autograft. Knee Surg Sports Traumatol Arthrosc 2014; 22: 2109-2120
  • 29 Risberg MA, Oiestad BE, Gunderson R, Aune AK, Engebretsen L, Culvenor A, Holm I. Changes in knee osteoarthritis, symptoms, and function after anterior cruciate ligament reconstruction: A 20-Year Prospective Follow-up Study. Am J Sports Med 2016; 44: 1215-1224
  • 30 Ruffilli A, Buda R, Pagliazzi G, Baldassarri M, Cavallo M, Luciani D, Ferranti E, Giannini S. Over-the-Top anterior cruciate ligament reconstruction using single- or double-strand hamstrings autograft. Orthopedics 2015; 38: e635-e643
  • 31 Tengman E, Brax Olofsson L, Nilsson KG, Tegner Y, Lundgren L, Hager CK. Anterior cruciate ligament injury after more than 20 years: I. Physical activity level and knee function. Scand J Med Sci Sports 2014; 24: e491-e500
  • 32 Tengman E, Brax Olofsson L, Stensdotter AK, Nilsson KG, Hager CK. Anterior cruciate ligament injury after more than 20 years. II. Concentric and eccentric knee muscle strength. Scand J Med Sci Sports 2014; 24: e501-e509
  • 33 Thompson S, Salmon L, Waller A, Linklater J, Roe J, Pinczewski L. Twenty-year outcomes of a longitudinal prospective evaluation of isolated endoscopic anterior cruciate ligament reconstruction with patellar tendon autografts. Am J Sports Med 2015; 43: 2164-2174
  • 34 Webster KE, Feller JA, Hartnett N, Leigh WB, Richmond AK. Comparison of patellar tendon and hamstring tendon anterior cruciate ligament reconstruction: a 15-year follow-up of a randomized controlled trial. Am J Sports Med 2016; 44: 83-90
  • 35 Culvenor AG, Cook JL, Collins NJ, Crossley KM. Is patellofemoral joint osteoarthritis an under-recognised outcome of anterior cruciate ligament reconstruction? A narrative literature review. Br J Sports Med 2013; 47: 66-70
  • 36 Harriss DJ, Macsween A, Atkinson G. Standards for ethics in sport and exercise science research: 2018 update. Int J Sports Med 2017; 38: 1126-1131
  • 37 Coleman BD, Khan KM, Maffulli N, Cook JL, Wark JD. Studies of surgical outcome after patellar tendinopathy: Clinical significance of methodological deficiencies and guidelines for future studies. Victorian Institute of Sport Tendon Study Group. Scand J Med Sci Sports 2000; 10: 2-11
  • 38 Tallon C, Coleman BD, Khan KM, Maffulli N. Outcome of surgery for chronic Achilles tendinopathy. A critical review. Am J Sports Med 2001; 29: 315-320
  • 39 Shrier I, Boivin JF, Steele RJ, Platt RW, Furlan A, Kakuma R, Brophy J, Rossignol M. Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles. Am J Epidemiol 2007; 166: 1203-1209
  • 40 Chen T, Zhang P, Chen J, Hua Y, Chen S. Long-term outcomes of anterior cruciate ligament reconstruction using either synthetics with remnant preservation or hamstring autografts: A 10-year longitudinal study. Am J Sports Med 2017; 45: 2739-2750
  • 41 Holm I, Oiestad BE, Risberg MA, Gunderson R, Aune AK. No differences in prevalence of osteoarthritis or function after open versus endoscopic technique for anterior cruciate ligament reconstruction: 12-year follow-up report of a randomized controlled trial. Am J Sports Med 2012; 40: 2492-2498
  • 42 Janssen RP, du Mee AW, van Valkenburg J, Sala HA, Tseng CM. Anterior cruciate ligament reconstruction with 4-strand hamstring autograft and accelerated rehabilitation: A 10-year prospective study on clinical results, knee osteoarthritis and its predictors. Knee Surg Sports Traumatol Arthrosc 2013; 21: 1977-1988
  • 43 Mascarenhas R, Tranovich M, Karpie JC, Irrgang JJ, Fu FH, Harner CD. Patellar tendon anterior cruciate ligament reconstruction in the high-demand patient: Evaluation of autograft versus allograft reconstruction. Arthroscopy 2010; 26 (9 Suppl) S58-S66
  • 44 Seon JK, Song EK, Park SJ. Osteoarthritis after anterior cruciate ligament reconstruction using a patellar tendon autograft. Int Orthop 2006; 30: 94-98
  • 45 Sutherland AG, Cooper K, Alexander LA, Nicol M, Smith FW, Scotland TR. The long-term functional and radiological outcome after open reconstruction of the anterior cruciate ligament. J Bone Joint Surg Br 2010; 92: 1096-1099
  • 46 van der Hart CP, van den Bekerom MP, Patt TW. The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament. J Orthop Surg Res 2008; 3: 24
  • 47 Harris KP, Driban JB, Sitler MR, Cattano NM, Balasubramanian E, Hootman JM. Tibiofemoral osteoarthritis after surgical or nonsurgical treatment of anterior cruciate ligament rupture: a systematic review. J Athl Train 2017; 52: 507-517
  • 48 Oiestad BE, Holm I, Engebretsen L, Aune AK, Gunderson R, Risberg MA. The prevalence of patellofemoral osteoarthritis 12 years after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2013; 21: 942-949
  • 49 Peat G, Duncan RC, Wood LR, Thomas E, Muller S. Clinical features of symptomatic patellofemoral joint osteoarthritis. Arthritis Res Ther 2012; 14: R63