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Pharmacopsychiatry 2020; 53(05): 235-236
DOI: 10.1055/a-1167-3267
DOI: 10.1055/a-1167-3267
Letter to the Editor
Case of Severe Acute-on-Chronic Lithium Intoxication with 8.6 mmol/l and Prompt Hemodialysis

Lithium has been the gold standard in the long-term treatment of bipolar disorder for more than 40 years [1]. Due to a narrow therapeutic index lithium intoxication still is a common but potentially avoidable clinical problem [2]. The possibility of SILENT-syndrome (syndrome of irreversible lithium-effectuated neurotoxicity) illustrates that prevention and optimal treatment of lithium intoxication is vitally important [3].
Key words
lithium intoxication - SILENT-syndrome - extracorproreal treatment - Bipolar disorder - lithiumPublication History
Received: 03 April 2020
Accepted: 24 April 2020
Article published online:
11 May 2020
© 2020. Thieme. All rights reserved.
© Georg Thieme Verlag KG
Stuttgart · New York
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