Abstract
Background and study aims Pancreatic cystic lesions are being increasingly recognized on cross-sectional imaging
and mucinous premalignant cysts represent one of the most prevalent types. Endoscopic
ultrasound (EUS)-guided chemoablation offers a safe and minimally invasive ablation
approach yet with limited efficacy. Patients who develop acute pancreatitis as a complication
of chemoablation with alcohol however experience ablation rates up to 100 %. This
evidence suggests that recruitment of the body’s immune system may represent an avenue
to significantly increase the efficacy of EUS-guided chemoablation. Here we illustrate
this immune-mediated tumor killing phenomenon through a case presentation at our institution.
