Nervenheilkunde, Table of Contents Nervenheilkunde 2021; 40(01/02): 6-12DOI: 10.1055/a-1246-0345 Editorial Psychiatrie im dritten Jahrzehnt des 21. Jahrhunderts Manfred Spitzer∗ Recommend Article Abstract Full Text References Literatur 1 AlQuraishi M. Protein-structure prediction gets real. Nature 2020; 577: 627-628 2 Anonymus. The shape of things to come. DeepMind’s latest AI could spark a medical revolution. New Scientist 2020; 248 3311 5 3 Ardila D, Kiraly AP, Bharadwaj S. et al End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine 2019; 25: 954-961 4 Averina OV, Zorkina YA, Yunes RA. et al Bacterial Metabolites of Human Gut Microbiota Correlating with Depression. International Journal of Molecular Sciences 2020; 21: 9234 5 Bleuler E. Dementia Praecox oder die Gruppe der Schizophrenien. Leipzig: Franz Deuticke; 1911 6 Chance FS, Aimone JB, Musuvathy SS. et al Crossing the Cleft: Communication Challenges Between Neuroscience and Artificial Intelligence. Front Comput Neurosci 2020; 14: 39 7 Esteva A, Kuprel B, Novoa RA. et al Dermatologist-level classification of skin cancer with deep neural networks. Nature 2017; 547: 115-118 8 Galton F. Composite portraits. Nature 1878; 18: 97-100 9 Galton F. Composite portraits, made by combining those of many different persons into a single, resultant figure. Journal of the Anthropological Institute 1879; 8: 132-144 10 Guyon A, Rousseau J, Bégin F-G. et al Base editing strategy allows insertion of the A673T mutation in APP gene to prevent the development of Alzheimer’s disease. bioRxiv 2020.10.27.357830 11 Hassabis D, Kumaran D, Summerfield C. et al Neuroscience-Inspired Artificial Intelligence. Neuron 2017; 95: 245-258 12 Hebert JC, Radford-Smith DE, Probert F. et al Mom’s diet matters: Maternal prebiotic intake in mice reduces anxiety and alters brain gene expression and the fecal microbiome in offspring. Brain Behav Immun 2020; S0889-1591 (20) 31548-8 13 Hermle L. Die Degenerationslehre in der Psychiatrie. Fortschr Neurol Psychiat 1986; 54: 69-79 14 Howgego J. AI chemist figures out how to legally clone expensive patented drugs. New Scientist. 2019: 3214 https://www.newscientist.com/article/mg24132143-500-ai-chemist-figures-out-how-to-legally-clone-expensive-patented-drugs/ 15 Jonsson T, Atwal JK, Steinberg S. et al A mutation 404 in APP protects against Alzheimer’s disease and age-related cognitive decline. Nature 2012; 488: 96-99 16 Jumper J. et al High Accuracy Protein Structure Prediction Using Deep Learning. In Fourteenth Critical Assessment of Techniques for Protein Structure Prediction Abstract Book. 2020 https://predictioncenter.org/casp14/doc/CASP14_Abstracts.pdf 17 Kanjilal S, Oberst M, Boominathan S. et al A decision algorithm to promote outpatient antimicrobial stewardship for uncomplicated urinary tract infection. Sci Transl Med. 2020: 12 18 Kraepelin E. Psychiatrie. Leipzig: Barth; 1899 19 Kretschmer E. Körperbau und Charakter. Untersuchungen zum Konstitutionsproblem und zur Lehre von den Temperamenten. Berlin: Springer; 1977 20 Lombroso C. Genio e follia; in deutscher Übersetzung: Genie und Irrsinn, erschienen. Stuttgart: Reclam; 1887 21 Lu MT, Ivanov A, Mayrhofer T. et al Deep Learning to Assess Long-term Mortality. From Chest Radiographs. JAMA Network Open 2019; 2 (07) e197416 22 Malan-Muller S, Valles-Colomer M, Raes J. et al The Gut Microbiome and Mental Health: Implications for Anxiety- and Trauma-Related Disorders. OMICS 2018; 22 (02) 90-107 23 Martina Sgritta M, Dooling SW, Buffington SA. et al Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder. Neuron 2019; 101: 246-259 24 Reardon S. Rise of Robot Radiologists. Nature 2019; 576: S55-S58 25 Rutledge R. Injury severity and probability of survival assessment in trauma patients using a predictive hierarchical network model derived from ICD-9 codes. J Trauma 1995; 38 (04) 590-601 26 Schneider K. Klinische Psychopahologie. Stuttgart: Thieme; 1946/1980 27 Senior AW, Evans R, Jumper J. et al Improved protein structure prediction using potentials from deep learning. Nature 2020; 577: 706-710 28 Silver D. et al Mastering the game of Go with deep neural networks and tree search. Nature 2016; 529: 484-489 29 Silver D. et al Mastering the game of Go without human knowledge. Natur 2017; 550: 345-359 30 Spitzer M, Hermle L. Von der Degeneration zur Antizipation: Systematische und wissenschaftliche Aspekte der Genetik neuro-psychiatrischer Erkrankungen. Nervenarzt 1995; 66: 187-196 31 Spitzer M. Go und die Moral in Südkorea. Nervenheilkunde 2016; 35: 287-291 32 Spitzer M. www (WeltWeite Werbung) und die Folgen. Nervenheilkunde 2018; 37: 303-311 33 Spitzer M. Meditation, Mäuse und Myelin. Nervenheilkunde 2018; 37: 745-748 34 Spitzer M. Psychotherapie im Mausmodell. Nervenheilkunde 2019; 38: 231-339 35 Spitzer M. Dissoziation bei Mensch und Maus. Nervenheilkunde 2020; 39: 847-854 36 Tat, The AlphaFold team. AlphaFold: a solution to a 50-year-old grand challenge in biology. Blog Post Research, 30.11.2020 https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology 37 Valles-Colomer M, Falony G, Darzi Y. et al Nat Microbiol. 2019; 4 (04) 623-632