Abstract
Background and study aims Various techniques have been described for flexible endoscopic therapy for Zenkerʼs
diverticulum (ZD). Objective methods to assess myotomy effectiveness are lacking.
We assessed the utility of impedance planimetry in flexible endoscopic ZD therapies
and correlation with a validated symptom score.
Patients and methods Patients undergoing endoscopic therapy for symptomatic ZD from February 2019 to March
2020 were included. Intraprocedural impedance planimetry was performed pre- and post-myotomy
to assess esophageal diameter and distensibility index (DI). Eating Assessment Tool
(EAT)-10 scores were assessed preintervention and post-intervention. Descriptive statistics
were calculated.
Results Thirteen patients (46 % women; mean age 80 years; 77 % peroral endoscopic myotomy
technique) were included. Technical and clinical success was 100 %. No adverse events
occurred. At 40 mL and 50 mL, the diameter improved (mean 2.3 mm and 2.6 mm, respectively).
At 40 mL and 50 mL, the DI improved (mean 1.0 mm2/mmHg and 1.8 mm2/mmHg, respectively). EAT-10 scores improved by a mean of 15 points. Mean follow-up
was 97 days.
Conclusions Intraprocedural impedance planimetry may provide objective data to define success
for flexible endoscopic ZD. Further research is required to corroborate these results.
