CC BY-NC-ND 4.0 · TumorDiagnostik & Therapie 2021; 42(01): 62-67
DOI: 10.1055/a-1334-2889
Thieme Onkologie aktuell

Lebensqualität nach Brustkrebs: Erfassung, Relevanz und effektive Interventionen

Quality of life after breast cancer: Assessment, relevance and effective interventions
Martina Schmidt
Abteilung Bewegung, Präventionsforschung und Krebs; Deutsches Krebsforschungszentrum (DKFZ) und Nationales Centrum für Tumorerkrankungen (NCT), Heidelberg [Division of Physical Activity, Prevention and Cancer; German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg]
Karen Steindorf
Abteilung Bewegung, Präventionsforschung und Krebs; Deutsches Krebsforschungszentrum (DKFZ) und Nationales Centrum für Tumorerkrankungen (NCT), Heidelberg [Division of Physical Activity, Prevention and Cancer; German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg]
› Author Affiliations


Gesundheitsbezogene Lebensqualität ist für Brustkrebsbetroffene in allen Stadien, sowohl während als auch mittel- und langfristig nach Abschluss der Therapie, von großer Relevanz. Bei Zulassungsstudien für neue Behandlungen sowie wissenschaftlichen Studien zum Vergleich verschiedener Therapien gewinnt Lebensqualität als Endpunkt zunehmend an Bedeutung. Neben einer kurzen globalen Einschätzung der Lebensqualität sollten weitere wichtige Patient-Reported Outcomes erhoben werden. Patientinnen mit Brustkrebs berichten häufig über Einschränkungen durch Fatigue, Schlafprobleme, sexuelle bzw. klimakterische Probleme, kognitive Probleme, psychische Probleme und Verlust an körperlicher Leistungsfähigkeit. Die Lebensqualität nach Brustkrebs könnte vermutlich weiter gesteigert werden, wenn Aufklärung, Screening und Behandlung dieser Symptome systematischer Bestandteil der onkologischen Versorgung würden.


Health-related quality of life is of great relevance for breast cancer patients at all stages, both during treatment and in the medium and long term after treatment. Quality of life is becoming increasingly important as an end point in licensing studies for new treatments and in scientific studies comparing different therapies. In addition to a brief global assessment of quality of life, other important patient-reported outcomes should be assessed. Patients with breast cancer often report limitations due to fatigue, sleep problems, sexual and/or menopausal problems, cognitive problems, mental problems and loss of physical performance. Quality of life after breast cancer could probably be further increased if education, screening and treatment of these symptoms were a systematic part of oncological care.

Publication History

Article published online:
28 January 2021

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