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Tierarztl Prax Ausg K Kleintiere Heimtiere 2021; 49(02): 142-147
DOI: 10.1055/a-1377-1008
Case Report

Diagnosis and successful treatment of an Austrian dog infected with Trypanosoma congolense forest type

Diagnose und erfolgreiche Behandlung einer Infektion mit Trypanosoma congolense forest type bei einem Hund in Österreich
Michael Leschnik
1   Department of Companion Animals and Horses, University of Veterinary Medicine Vienna, Austria
,
Katja Silbermayr
2   Department of Pathobiology, Institute of Parasitology, University of Veterinary Medicine Vienna, Austria
,
Abigail Guija
4   Department of Pathobiology, Central Laboratory, University of Veterinary Medicine Vienna, Austria
,
Barbara Nell
1   Department of Companion Animals and Horses, University of Veterinary Medicine Vienna, Austria
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Abstract

Canine African Trypanosomosis (CAT) is a rarely described disease with frequently lethal outcome. A 5-year-old female mongrel dog weighing 22 kg was presented in Austria due to unilateral uveitis, pancytopenia, and anorexia 4 months after return from a trip through Western Africa. Trypanosoma spp. flagellates were detected in a blood smear and identified as Trypanosoma congolense forest type by PCR. Initial treatment with imidocarb and miltefosine led to clinical improvement but only isometamidium chloride hydrochloride applied intramuscularly led to complete eradication of the pathogen from the dog’s blood 4 months later.

Zusammenfassung

Die kanine afrikanische Trypanosomosis wurde bislang selten beschrieben mit zumeist letalem Ausgang. Eine 5 Jahre alte Mischlingshündin mit einem Körpergewicht von 22 kg wurde in Österreich wegen einer einseitigen Uveitis, einer Panzytopenie und Anorexie 4 Monate nach der Rückkehr von einem Aufenthalt in Westafrika vorgestellt. Im Blutausstrich wurden Trypanosoma spp.-Flagellaten gefunden und mittels PCR als Trypanosoma congolense forest type identifiziert. Die initiale Behandlung mit Imidocarb und Miltefosin bewirkte eine klinische Verbesserung, aber erst die intramuskuläre Applikation von Isometamidiumchlorid-Hydrochlorid führte zur Erregerelimination 4 Monate nach der Diagnosestellung.

Key words

Canine African trypanosomosis - uveitis - imidocarb - miltefosine - isometamidium

Schlüsselwörter

Kanine afrikanische Trypanosomiasis - Uveitis - Imidocarb - Miltefosin - Isometamidium


Publication History

Received: 21 April 2020

Accepted: 01 September 2020

Article published online:
26 April 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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