Sind röntgenologische Scoring-Methoden als Parameter zur Verlaufsbeurteilung der rheumatoiden Arthritis noch zeitgemäß?

Zusammenfassung

Die radiologische Progression beschreibt das Ausmaß der Gelenkzerstörung im Verlauf einer rheumatoiden Arthritis. Zur Quantifizierung der radiologischen Progression werden Scoring-Methoden (z. B. van der Heijde Modifikation des Sharp-Score) eingesetzt. In verschiedenen Studien zu biologischen- bzw. target-synthetischen Disease Modifying Anti-Rheumatic Drugs gelang nur unzureichend eine Differenzierung der radiologischen Progression. Zudem finden die Scores oft keinen routinemäßigen Einsatz in der klinischen Entscheidungsfindung. Durch die computerbasierte Analyse von Handröntgenaufnahmen ist eine valide Quantifizierung der radiologischen Progression und die zuverlässige Bewertung von Therapieeffekten möglich. Somit stellen die computerbasierten Methoden eine vielversprechende Alternative in der Quantifizierung der radiologischen Progression dar.

Abstract

Radiographic progression is used to assess joint destruction in rheumatoid arthritis. Different scoring methods (e. g. van der Heijde modification of the Sharp Score) are established for the quantification of radiographic progression. In several studies focusing on biological and target-synthetic disease-modifying anti-rheumatic drugs, these scores have not been able to differentiate radiographic progression in detail. Additionally, the scores are often not used in the clinical routine. Computer-based techniques offer a valid quantification of radiographic progression and a reliable assessment of therapeutic effects. Consequently, computer-based techniques seem to be a promising alternative for the quantification of radiographic progression.

Schlüsselwörter

Radiologische Progression - Rheumatoide Arthritis - Röntgenbild - Diagnostik - Scoring

Key words

radiographic progression - rheumatoid arthritis - x-ray - diagnostic - scoring

Publication History

Article published online:
08 April 2021

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