Gastroenterologie up2date, Inhaltsverzeichnis Gastroenterologie up2date 2021; 17(02): 110-114DOI: 10.1055/a-1402-5177 Studienreferate Kommentar Authors Artikel empfehlen Abstract Artikel einzeln kaufen(opens in new window) Alle Artikel dieser Rubrik(opens in new window) Kommentar zu diesem Artikel:Oxaliplatin-Fluorpyrimidin-Kombi: Standard bei MSI-Darmkrebs im Stadium III?Gastroenterologie up2date 2021; 17(02): 110-110DOI: 10.1055/a-1402-5154 Volltext Referenzen Literatur 1 Goldstein J, Tran B, Ensor J. et al. Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H). Ann Oncol 2014; 25: 1032-1038 2 Le DT, Uram JN, Wang H. et al. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. N Engl J Med 2015; 372: 2509-2520 3 Le DT, Durham JN, Smith KN. et al. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science 2017; 357: 409-413 4 Le DT, Kim TW, Van Cutsem E. et al. Phase II open-label study of pembrolizumab in treatment-refractory, microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer. J Clin Oncol 2020; 38: 11-19 5 Overman MJ, Lonardi S, Wong KYM. et al. Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer. J Clin Oncol 2018; 36: 773-779 6 Ludford K, Cohen R, Svrcek M. et al. Pathological Tumor Response Following Immune Checkpoint Blockade for Deficient Mismatch Repair Advanced Colorectal Cancer. J Natl Cancer Inst 2021; 113: 208-211 7 Shiu K-K, Andre T, Kim TW. et al. KEYNOTE-177: Phase III randomized study of pembrolizumab versus chemotherapy for microsatellite instability-high advanced colorectal cancer. J Clin Oncol 2021; 39