Zeitschrift für Gastroenterologie, Table of Contents Z Gastroenterol 2021; 59(07): 777-781DOI: 10.1055/a-1528-8317 Mitteilungen der DGVS Gemeinsame Stellungnahme der DGHO, AIO, DEGRO und DGVS zur Nutzenbewertung von Nivolumab (Plattenepithelkarzinom des Ösophagus, nach Vorbehandlung) Recommend Article Abstract Buy Article(opens in new window) Full Text References Literatur 1 S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus. Dezember 2018 https://www.awmf.org/leitlinien/detail/ll/021-023OL.html 2 Stahl M. et al Ösophaguskarzinom, Onkopedia. Dezember 2018 https://www.onkope-dia.com/de/onkopedia/guidelines/oesophaguskarzinom/@@guideline/html/index.html 3 Gesellschaft der epidemiologischen Krebsregister in Deutschland/Robert Koch-Institut. Krebs in Deutschland 2015–2016, Häufigkeiten und Trends: Ösophagus. 2020 12. Ausgabe. 28-30 4 Moehler M, Maderer A, Thuss-Patience PC. et al. Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER). Ann Oncol 2020; 31: 228-235 5 Lagergren J, Smyth E, Cunningham D. et al. Oesophageal cancer. Lancet 2017; 390: 2383-2396 6 Conroy T, Galais M-P, Raoul J-L. et al. Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5 / ACCORD17): final results of a randomised, phase 2/3 trial. Lancet Oncol 2014; 15: 305-314 7 Adenis A, Bennouna J, Etienne P. et al Continuation versus discontinuation of first-line chemotherapy in patients with metastatic squamous cell oesophageal cancer: A randomised phase II trial (E-DIS). Eur J Cancer 2019; 111: 12-20 . DOI: Thallinger CMR, Raderer M, Hejna M. Esophageal cancer: a critical evaluation of systemic second-line therapy. J Clin Oncol. 10. Dezember 29:4709–4714, 2011. DOI:10.1200/JCO.2011.36.7599 8 Abraham P, Gricar J, Zhang Y. et al. Real-World Treatment Patterns and Outcomes in Patients Receiving Second-Line Therapy for Advanced/Metastatic Esophageal Squamous Cell Carcinoma. Adv Ther 2020; 37: 3392-3403 9 Kato K, Cho B, Takahashi M. et al. Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase III trial. Lancet Oncol 2019; 20: 1506-1517 10 Kojima T, Shah MA, Muro K. et al. Randomized Phase III KEYNOTE-181 Study of Pembroli- zumab Versus Chemotherapy in Advanced Esophageal Cancer. J Clin Oncol 2020; 38: 4138-4148 11 Cherny NI, Sullivan R, Dafni U. et al. A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS). Ann Oncol 2015; 26: 1547-1573 12 Cherny NI, Dafni U, Bogaerts J. et al. ESMO-Magnitude of Clinical Benefit Scale version1.1. Ann Oncol 2017; 28: 2340-2366