Klin Padiatr 2022; 234(02): 74-80
DOI: 10.1055/a-1554-5699
Original Article

Cycled Lighting Versus Continuous Near Darkness in Preterm Infants: A Randomized Controlled Trial

Zyklische Beleuchtung versus kontinuierliche Dunkelheit bei Frühgeborenen: Eine randomisierte kontrollierte Studie
Sema Arayici
1   Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Gulsum Kadioglu Simsek
2   Division of Neonatology, Ankara City Hospital, Ministry of Health, Ankara, Turkey.
Nurdan Uras
3   Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Istinye University, Istanbul, Turkey.
Mehmet Yekta Oncel
4   Department of Pediatrics, Division of Neonatology, Faculty of Medicine, İzmir Katip Çelebi University, İzmir, Turkey.
Fuat Emre Canpolat
2   Division of Neonatology, Ankara City Hospital, Ministry of Health, Ankara, Turkey.
Serife Suna Oguz
2   Division of Neonatology, Ankara City Hospital, Ministry of Health, Ankara, Turkey.
› Author Affiliations


Objective To compare the effectiveness of cycled lighting (CL) or continuous near darkness (CND) on weight in preterm infants.

Study Design Total 147 infants with a gestational age 25–32 weeks and/or a birth weight 750–1500 g were included in the study. The infants were classified into two groups: CL and CND. Weight on postnatal day 14, weight at corrected 35 weeks, mean rectal temperature and serum growth hormone, cortisol, melatonin levels at 35 weeks’ post menstrual age (PMA), weekly weight gain, full enteral feeding time, duration of mechanical ventilation, retinopathy of prematurity (ROP), length of stay in the hospital, weight and length at three and six months corrected age were compared between the groups.

Results There were no differences between weights on postnatal day 14. Anthropometric parameters and mean rectal temperatures of groups also were not different at 35 weeks’ PMA. There were no differences among the groups in duration of full enteral feeding time, length of stay in hospitalization, duration of mechanical ventilation, ROP and anthropometric parameters. Further, serum growth hormone, cortisol, and melatonin levels were similar between the groups at 35 weeks’ PMA.

Conclusion CL and CND did not have any advantages over each other.


Ziel Vergleich der Wirksamkeit von zyklischer Beleuchtung (CL) oder kontinuierlicher Dunkelheit (CND) auf das Gewicht bei Frühgeborenen.

Studiendesign Insgesamt 147 Säuglinge mit einem Gestationsalter von 25 bis 32 Wochen und / oder einem Geburtsgewicht von 750 bis 1500 g wurden in die Studie eingeschlossen. Die Säuglinge wurden in zwei Gruppen eingeteilt: CL und CND. Gewicht am 14. postnatalen Tag, Gewicht nach korrigierten 35 Wochen, mittlere Rektaltemperatur und Serumwachstumshormon, Cortisol, Melatoninspiegel 35 Wochen nach der Menstruation (PMA), wöchentliche Gewichtszunahme, volle enterale Fütterungszeit, Dauer der mechanischen Beatmung, Retinopathie Frühgeborenen (ROP), Verweildauer im Krankenhaus, Gewicht und Dauer im korrigierten Alter von drei und sechs Monaten wurden zwischen den Gruppen verglichen.

Ergebnisse Am postnatalen Tag 14 gab es keine Unterschiede zwischen den Gewichten. Die anthropometrischen Parameter und die mittleren Rektaltemperaturen der Gruppen unterschieden sich auch nach 35 Wochen PMA nicht. Es gab keine Unterschiede zwischen den Gruppen hinsichtlich der Dauer der vollständigen enteralen Fütterungszeit, der Dauer des Krankenhausaufenthalts, der Dauer der mechanischen Beatmung, der ROP und der anthropometrischen Parameter. Darüber hinaus waren die Serumwachstumshormon-, Cortisol- und Melatoninspiegel zwischen den Gruppen nach 35 Wochen PMA ähnlich.

Schlussfolgerung CL und CND hatten keine Vorteile gegenüber einander.

Publication History

Article published online:
01 September 2021

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