Abstract
This study aimed to analyze the benefits of a lower-limb fast-velocity concentric
resistance training on rate of force development, mobility, and quality of life
in people with Multiple Sclerosis. A randomized controlled trial was conducted
in 30 people with Multiple Sclerosis, who were randomly assigned to either an
experimental (n=18) or a control (n=12) group. The experimental
group carried out 10-weeks of fast-velocity concentric resistance training,
while the control group did not perform any intervention. Early and late rate of
force development during knee extension in both legs, sit-to-stand and Timed Up
and Go tests and quality life questionnaire were evaluated before and after
intervention. The training program evoked an increase in early rate of force
development in experimental group (0–30; Rightleg:
63.9%, p<0.001; ES=-1.4; Leftleg:
52.7%, p<0.001; ES=-1.0) compared to control group
(showed modest increases). Furthermore, experimental group improved mobility
after training (Sit-to-stand: 22.2%, p<0.001; ES=1.0;
Timed Up and Go Test: 10.1%, p<0.001; ES=1.1) and
increased the perception of quality of life after training, while control showed
no changes. The fast-velocity concentric resistance training has the potential
to improve early rate of force development and mobility after 10-weeks of
training. In addition, the increase in self-perceived quality of life following
this training modality demonstrates promising results in the Multiple Sclerosis
population.
Key words
neurodegenerative disorders - exercise - strength - neuromuscular
