Chemosaturation of the Liver – an Update

Abstract

Background Percutaneous hepatic perfusion (CS-PHP) is a treatment option for primary and secondary liver neoplasms and subject of intensive research. This present article provides an overview of CS-PHP regarding patient safety, feasibility and effectiveness based on recent studies.

Method We performed a PubMed search including the search terms chemosaturation, hepatic chemosaturation, percutaneous perfusion and melphalan.

Results and conclusion CS-PHP is a promising procedure for the treatment of uveal melanoma and cholangiocellular carcinoma. There are insufficient data regarding the effectiveness of CS-PHP with respect to other tumor entities. Since CS-PHP can be accompanied by multiple transient side effects and complications, close interdisciplinary cooperation is necessary.

Key Points:

• Chemosaturation of the liver is a safe procedure.

• CS-PHP is a potent therapy for hepatic metastatic ocular melanoma and cholangiocellular carcinoma.

• The procedure requires close interdisciplinary coordination.

• CS-PHP is a repeatable and thus long-term therapeutic option for some patients.

Citation Format

• Ebel S, Struck MF, van Boemmel F et al. Chemosaturation of the Liver – an Update. Fortschr Röntgenstr 2023; 195: 30 – 37

Key words

abdomen - hematologic - angiography - interventional procedures

Publication History

Received: 20 September 2021

Accepted: 05 May 2022

Article published online:
17 August 2022

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