Dtsch Med Wochenschr 2022; 147(16): 1068-1077
DOI: 10.1055/a-1868-9164

Metabolisches Syndrom und Krebsrisiko

Metabolic syndrome and cancer risk
Hans Scherübl

Krebs zählt zu den führenden Todesursachen beim metabolischen Syndrom (MetS). Je mehr Komponenten des metabolischen Syndroms jemand hat, desto stärker steigt das Tumorrisiko, z. B. Karzinome des Dickdarms. Bei adipösen MetS-Patienten kann die Gewichtsreduktion das Krebsrisiko senken. Dem MetS vorzubeugen und regelmäßig an Vorsorgeuntersuchungen teilzunehmen ist wichtig und verringert das Risiko, an Krebs zu erkranken und daran zu versterben.


Cancer has become a leading cause of death among patients with metabolic syndrome (MetS). The more components of MetS a patient has, the higher his risk of cancer. MetS is causally associated with colorectal, pancreatic, gallbladder, biliary, hepatocellular, gastric, esophageal, thyroid, breast, endometrial and renal cell cancers. MetS increases cancer mortality up to 2,4-fold. Intentional long-term weight loss reduces the excess cancer risk of obese MetS-patients. Both a low-risk lifestyle and cancer screening are effective and decrease the burden of cancer.

Publication History

Article published online:
15 August 2022

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