Open Access
CC BY-NC-ND 4.0 · Horm Metab Res 2022; 54(08): 503-509
DOI: 10.1055/a-1878-9566
Review

Diabetes and COVID-19: Short- and Long-Term Consequences

Authors

  • Charlotte Steenblock

    1   Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
  • Mohamed Hassanein

    2   Department of Diabetes and Endocrinology, Dubai Hospital, Dubai, United Arab Emirates
  • Emran G. Khan

    3   Endocrinology and Diabetology, King’s College Hospital London, Dubai, United Arab Emirates
  • Mohamad Yaman

    4   Building 6, Nesmah Technology, Dubai, United Arab Emirates
  • Margrit Kamel

    1   Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
  • Mahmoud Barbir

    5   Department of Cardiology, Harefield Hospital, Harefield, United Kingdom of Great Britain and Northern Ireland
  • Dietrich E. Lorke

    6   Department of Anatomy and Cellular Biology, Khalifa University, Abu Dhabi, United Arab Emirates
  • John A. Rock

    7   College of Medicine & Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates
  • Dean Everett

    8   Department of Pathology and Infectious Diseases, Khalifa University, Abu Dhabi, United Arab Emirates
  • Saqipi Bejtullah

    9   Research Unit, College Heimerer, Prishtina, Republic of Kosovo
  • Adrian Heimerer

    9   Research Unit, College Heimerer, Prishtina, Republic of Kosovo
  • Ermal Tahirukaj

    1   Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
  • Petrit Beqiri

    9   Research Unit, College Heimerer, Prishtina, Republic of Kosovo
  • Stefan R. Bornstein

    1   Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
    10   School of Cardiovascular and Metabolic Medicine and Sciences, Faculty of Life Sciences & Medicine, King’s College London, London, UK
Preview

Abstract

When the corona pandemic commenced more than two years ago, it was quickly recognized that people with metabolic diseases show an augmented risk of severe COVID-19 and an increased mortality compared to people without these comorbidities. Furthermore, an infection with SARS-CoV-2 has been shown to lead to an aggravation of metabolic diseases and in single cases to new-onset metabolic disorders. In addition to the increased risk for people with diabetes in the acute phase of COVID-19, this patient group also seems to be more often affected by long-COVID and to experience more long-term consequences than people without diabetes. The mechanisms behind these discrepancies between people with and without diabetes in relation to COVID-19 are not completely understood yet and will require further research and follow-up studies during the following years. In the current review, we discuss why patients with diabetes have this higher risk of developing severe COVID-19 symptoms not only in the acute phase of the disease but also in relation to long-COVID, vaccine breakthrough infections and re-infections. Furthermore, we discuss the effects of lockdown on glycemic control.



Publication History

Received: 16 March 2022

Accepted after revision: 04 April 2022

Accepted Manuscript online:
20 June 2022

Article published online:
09 August 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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