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Semin Neurol 2022; 42(06): 708-715
DOI: 10.1055/a-1985-0460
Review Article

Challenging Cases in Neurology: Neurologic Complications of COVID-19

Lucas Horta
1   Department of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
,
Ava Bakhtyari   *
1   Department of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
,
Tatiana Greige   *
1   Department of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
,
Pria Anand 
1   Department of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
› Author Affiliations Funding None.
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Abstract

Since the first reported cases of pneumonia in December 2019, coronavirus disease 2019 (COVID-19) has rapidly become recognized as a multisystem illness, with known effects on virtually every organ system. In particular, neurologic complications of COVID-19 have been reported since the beginning of the pandemic in both ambulatory patients with mild disease and critically ill patients. Although it remains unclear whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has the potential to directly invade the central nervous system, strokes and other neurovascular complications, sequelae of critical illness and metabolic derangements, parainfectious inflammatory disorders, and a poorly understood post-COVID syndrome have all been reported in patients with COVID-19. Here, we describe cases representing a diverse range of neurologic complications in patients infected with COVID-19.

Keywords

COVID-19 - encephalitis - GAD-65 encephalitis - osmotic demyelination syndrome - anterior biopercular syndrome

* Equal contribution.




Publication History

Accepted Manuscript online:
23 November 2022

Article published online:
27 December 2022

© 2022. Thieme. All rights reserved.

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