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Int J Sports Med 2023; 44(07): 496-504
DOI: 10.1055/a-2016-5376
Physiology & Biochemistry

Circulating Fatty Acid-binding Protein 4 Response to Acute Aerobic Exercise in Healthy Men

Shigeharu Numao 
1   Sports and Life Sciences, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan
,
Ryota Uchida
2   Graduate School of Physical Education, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan
,
Takashi Kurosaki
2   Graduate School of Physical Education, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan
,
Masaki Nakagaichi
1   Sports and Life Sciences, National Institute of Fitness and Sports in Kanoya, Kagoshima, Japan
› Author Affiliations Funding Information The authors thank all the participants of the present study. The Japan Society Promotion of Science Grant-in-Aid for Scientific Research (C) — JP18K10838
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Correction: Circulating Fatty Acid-binding Protein 4 Response to Acute Aerobic Exercise in Healthy MenInt J Sports Med 2023; 44(07): e1-e1
DOI: 10.1055/a-2092-0045

Abstract

This study aimed to investigate the association between changes in FABP4 concentration and hormone and metabolite levels during and after acute low- and moderate-intensity aerobic exercise in healthy men. Eleven healthy men (24.4±1.4 years) were administered three trials in random order: 1) low-intensity aerobic exercise trial (LE trial; acute exercise at 40% peak oxygen uptake [Vo2peak]+bed rest), 2) moderate-intensity aerobic exercise trial (ME trial: acute exercise at 60%Vo2peak+bed rest), and 3) bed rest (Con trial). Expired gas and venous blood samples were collected at baseline, and immediately, 30 and 60 min after exercise, and substrate oxidation and hormone, metabolite, and FABP4 concentrations were measured. FABP4 concentration did not increase during aerobic exercise in LE and ME trials (p>0.05). However, FABP4 concentration significantly increased after the acute aerobic exercise in both the LE and ME trials (p≤0.003). Increased FABP4 concentration after acute exercise was not correlated with adrenaline, noradrenaline, other hormone, and metabolite concentration changes. These findings suggest that FABP4 concentration increases after acute aerobic exercise independently of exercise intensity. Furthermore, increased FABP4 concentration after acute aerobic exercise may not be involved in the magnitude of adrenaline, noradrenaline, and lipolytic response.

Key words

fatty acid-binding protein - glucose - lipolysis - catecholamine - troponin T

Supplementary Material



Publication History

Received: 27 October 2022

Accepted: 17 January 2023

Accepted Manuscript online:
19 January 2023

Article published online:
21 April 2023

© 2023. Thieme. All rights reserved.

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Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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