Facial Plast Surg 2023; 39(05): 466-473
DOI: 10.1055/a-2113-5023
Original Article

Translational Research Techniques for the Facial Plastic Surgeon: An Overview

Authors

  • William Mason

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
  • Albert M. Levin

    2   Department of Public Health Science, Henry Ford Health, Detroit, Michigan
    3   Center for Bioinformatics, Henry Ford Health, Detroit, Michigan
  • Katherine Buhl

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
  • Takahiro Ouchi

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
  • Bianca Parker

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
  • Jessica Tan

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
  • Nureddin Ashammakhi

    4   Institute for Quantitative Health Science and Engineering, Michigan State University, Michigan
    5   Department of Biomedical Engineering, College of Engineering, Michigan State University, Michigan
    6   College of Human Medicine, Michigan State University, Michigan
  • Lamont R. Jones

    1   Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan

Funding The authors acknowledge the funding received from the National Institutes of Health (1UG3TR003148-01) (N.A.).
Preview

Abstract

The field of facial plastic and reconstructive surgery (FPRS) is an incredibly diverse, multispecialty field that seeks innovative and novel solutions for the management of physical defects on the head and neck. To aid in the advancement of medical and surgical treatments for these defects, there has been a recent emphasis on the importance of translational research. With recent technological advancements, there are now a myriad of research techniques that are widely accessible for physician and scientist use in translational research. Such techniques include integrated multiomics, advanced cell culture and microfluidic tissue models, established animal models, and emerging computer models generated using bioinformatics. This study discusses these various research techniques and how they have and can be used for research in the context of various important diseases within the field of FPRS.



Publication History

Accepted Manuscript online:
20 June 2023

Article published online:
20 July 2023

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