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DOI: 10.1055/a-2122-6121
A Case Report of Madelung's Disease

Abstract
Madelung's disease (MD) is a rare disease characterized by diffuse, nonencapsulated, multiple fat masses in different areas of the body. In this case report, we present a case of MD in Asia and its management. A 66-year-old man with a history of hypertension presented with massive growth of soft tissue around the neck, breasts, upper back, and lower abdomen. Preoperative magnetic resonance imaging revealed remarkably hypertrophic fat tissue around the neck and anterior chest was wall, which consistent with the diagnosis of MD. Multiple linear incisions were made on the neck and 763, 186, 635 g of posterior, right, and left fat tissues were excised, respectively. A single wide, transverse incision was done to excise 1,072 g of fat from the upper back. Masses of both breasts were excised, preserving the inferior pedicle, weighing 1,086 (right) and 1,164 g (left). The recovery was optimal and the patient was discharged without complications. In this case, we excised the adipose masses as much as possible and improved contour and symmetry. However, the fat infiltrations in the patient were diffusely distributed, making total fat excision difficult. This rare case report may help in managing patients with MD.
Authors' Contributions
Conceptualization: Y.H.K.; data curation: B.H.L.; formal analysis: B.H.L., S.O.P., Y.M.L.; writing—original draft: B.H.L.; writing—review and editing: L.S.C., Y.H.K. All authors have read and approved the final manuscript.
Ethical Approval
This study was performed in accordance with the principles of the Declaration of Helsinki. The study was approved for exemption by the Institutional Review Board of Hanyang University Hospital (IRB exemption no. 2022-11-013).
Patient Consent
The patient provided written informed consent for the publication and use of images.
Publication History
Received: 26 January 2023
Accepted: 30 June 2023
Accepted Manuscript online:
04 July 2023
Article published online:
05 October 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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