Open Access
CC BY 4.0 · Arch Plast Surg 2024; 51(02): 196-201
DOI: 10.1055/a-2222-1226
Pediatric/Craniomilofacial/Head & Neck
Case Report

The Nevus Lipomatosus Superficialis of Face: A Case Report and Literature Review

Jae-Won Yang 
1   Gangnam Jaejun Plastic Clinic, Pyeongtaek-si, Gyeongi-do, Korea
,
Mi-Ok Park 
2   MioGreensumer Pathology Clinic, Incheon City, Korea
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Abstract

Nevus lipomatosus superficialis (NLS) is a hamartoma of adipose tissue, rarely reported in the past 100 years. We treated one case, and we conducted a systematic review of the literature. A 41-year-old man presented with a cutaneous multinodular lesion in the posterior region near the right auricle. The lesion was excised and examined histopathologically. To review the literature, we searched PubMed with the keyword “NLS.” The search was limited to articles written in English and whose full text was available. We analyzed the following data: year of report, nation of corresponding author, sex of patient, age at onset, duration of disease, location of lesion, type of lesion, associated symptoms, pathological findings, and treatment. Of 158 relevant articles in PubMed, 112 fulfilled our inclusion criteria; these referred to a total of 149 cases (cases with insufficient clinical information were excluded). In rare cases, the diagnosis of NLS was confirmed when the lesion coexisted with sebaceous trichofolliculoma and Demodex infestation. Clinical awareness for NLS has increased recently. NLS is an indolent and asymptomatic benign neoplasm that may exhibit malignant behavior in terms of huge lesion size and specific anatomical location. Early detection and curative treatment should be promoted.

Keywords

nevus lipomatosus superficialis - sebaceous trichofolliculoma - Demodex - hamartoma

Authors' Contributions

Conceptualization: M.O.P. and J.W.Y.

Formal analysis: J.W.Y.

Project administration: J.W.Y.

Writing-original draft: J.W.Y. and M.O.P.

Writing-review & editing: J.W.Y. and M.O.P.


Ethical Approval

This study was approved by the Institutional Review Board of the Korea National Institute for Bioethics Policy (IRB No. P01-202305-01-041) and was conducted in accordance with the tenets of the Declaration of Helsinki. Written informed consent to publish the case was obtained from the patient.


Patient Consent

Written informed consent to publish the case was obtained from the patient.




Publication History

Received: 03 August 2023

Accepted: 24 November 2023

Accepted Manuscript online:
04 December 2023

Article published online:
24 January 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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