The Difunctionalization of Alkenes Completed by DMTSM and CF3SO2Na without Metal Catalysts

Siwei Shen; Jinzhao Gao; Xiaofeng Luo; Tianqiang Wang; Peihua Liu; Rulong Yan

doi:10.1055/a-2283-5928

Synlett, Table of Contents

Synlett 2024; 35(17): 2032-2036
DOI: 10.1055/a-2283-5928

letter

The Difunctionalization of Alkenes Completed by DMTSM and CF₃SO₂Na without Metal Catalysts

Authors

Siwei Shen

^aState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 73000, Gansu, P. R. of China
Jinzhao Gao

^aState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 73000, Gansu, P. R. of China
Xiaofeng Luo

^bChengdu Guibao Science and Technology Co, Ltd, Chengdu 610041 Sichuan, P. R. of China
Tianqiang Wang

^bChengdu Guibao Science and Technology Co, Ltd, Chengdu 610041 Sichuan, P. R. of China
Peihua Liu

^cResearch Institute of Oil and Gas Technology of Changqing Oilfield Company, Xian 710018, Shanxi, P. R. of China
Rulong Yan∗

^aState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 73000, Gansu, P. R. of China

Abstract

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Abstract

The electrophilic thiolation of alkenes initiated by DMTSM and the addition of CF₃SO₂Na in one pot has been developed. This reaction also can be extended to ArSO₂Na. This protocol features a good substrate scope, simple procedures, and mild reaction conditions and affords the desired products in moderate yields without metal catalysts.

Key words

DMTSM - CF₃SO₂Na - difunctionalization

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References

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Supplementary Material

Supporting Information (PDF)