Int J Sports Med 2025; 46(02): 69-78
DOI: 10.1055/a-2433-3930
Review

Psychophysiological markers of athlete burnout: a call to arms

1   Department for Health, Faculty of Humanities and Social Sciences, University of Bath, Bath, United Kingdom of Great Britain and Northern Ireland
,
Sandrine Isoard-Gautheur
2   Faculty of Humanities, Health, Sport, and Societies, Universite Grenoble Alpes, Saint-Martin-dʼHeres, France (Ringgold ID: RIN27015)
,
Henrik Gustafsson
3   Department of Educational Studies, Karlstad University, Karlstad, Sweden (Ringgold ID: RIN4209)
4   Department of Sport and Social Sciences, Norwegian School of Sports Sciences, Oslo, Norway (Ringgold ID: RIN25567)
› Author Affiliations
Supported by: University of Bath

Abstract

Burnout is a growing problem in high-performance sport and has negative consequences for athletes (e.g., mental ill-health). It is therefore important to effectively monitor athlete burnout to aid intervention efforts. While self-report measures are available (e.g., athlete burnout questionnaire), the limitations associated with these measures (e.g., social desirability bias) means that objective physiological markers may also be useful. Thus, this article critically discusses potential biomarkers of athlete burnout, drawing on research inside and outside of sport to offer an overview of the current state-of-the-art in this research area. First, it outlines what athlete burnout is, its deleterious consequences, and discusses existing psychological assessments. The article then critically discusses literature on hypothalamic-pituitary-adrenal axis (e.g., salivary cortisol) and autonomic nervous system (e.g., heart rate variability) indices of burnout, highlighting some promising biomarkers for future research (e.g., salivary cortisol at bedtime, vagally-mediated heart rate variability at rest). Finally, the article concludes by highlighting key considerations and offering recommendations for future research (e.g., use of more homogenous methods in assessing burnout and physiological parameters). As a result, the intention of this article is to spark more higher quality research on the psychophysiology of athlete burnout, thereby helping tackle this prominent issue in high-performance sport.



Publication History

Received: 05 January 2024

Accepted after revision: 02 October 2024

Accepted Manuscript online:
02 October 2024

Article published online:
20 November 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Freudenberger HJ. Staff burn-out. J Soc Issues 1974; 30: 159-165
  • 2 Maslach C. ed. Burnout: The cost of caring. New York: Prentice-Hall; 1982
  • 3 Freudenberger HJ. The staff burn-out syndrome in alternative institutions. Psychother-Theor Res 1975; 12: 73-82
  • 4 Feigley DA. Psychological burnout in high-level athletes. Phys Sportsmed 1984; 12: 108-119
  • 5 Dale J, Weinberg R. Burnout in sport: A review and critique. J Appl Sport Psychol 1990; 2: 67-83
  • 6 Raedeke TD. Is athlete burnout more than just stress? A sport commitment perspective. J Sport Exercise Psy 1997; 19: 396-417
  • 7 Gerber M, Gustafsson H, Seelig H. et al. Usefulness of the Athlete Burnout Questionnaire (ABQ) as a screening tool for the detection of clinically relevant burnout symptoms among young elite athletes. Psychol Sport Exerc 2018; 39: 104-113
  • 8 Gustafsson H, Kenttä G, Hassmén P. et al. Prevalence of burnout in competitive adolescent athletes. TSP 2007; 21: 21-37
  • 9 Madigan DJ, Olsson LF, Hill AP. et al. Athlete burnout symptoms are increasing: A cross-temporal meta-analysis of average levels from 1997 to 2019. J Sport Exercise Psy 2022; 44: 153-168
  • 10 Isoard-Gautheur S, Trouilloud D, Gustafsson H. et al. Associations between the perceived quality of the coach-athlete relationship and athlete burnout: An examination of the mediating role of achievement goals. Psychol Sport Exerc 2016; 22: 210-217
  • 11 Glandorf HL, Madigan DJ, Kavanagh O. et al. Mental and physical health outcomes of burnout in athletes: A systematic review and meta-analysis. Int Rev Sport Exer P 2023;
  • 12 Gustafsson H, DeFreese JD, Madigan DJ. Athlete burnout: Review and recommendations. Curr Opin Psychol 2017; 16: 109-113
  • 13 Shirom A, Melamed S. A comparison of the construct validity of two burnout measures in two groups of professionals. Int J Stress Manag 2006; 13: 176-200 psycnet.apa.org/
  • 14 Raedeke TD, Smith AL. Development and preliminary validation of an athlete burnout measure. J Sport Exercise Psy 2001; 23: 281-306
  • 15 Madigan DJ, Gustafsson H, Smith A. et al. The BASES expert statement on burnout in sport. Sport Exerc Scient 2019; 61: 6-7 www.bases.org.uk/imgs/tses___issue_61_autumn_19_expert_statement_online__pages_579.pdf
  • 16 Lonsdale C, Hodge K, Jackson SA. Athlete engagement: II. Developmental and initial validation of the Athlete Engagement Questionnaire. Int J Sport Psychol 2007; 38: 471-492
  • 17 Isoard-Gautheur S, Martinent G, Guillet-Descas E. et al. Development and evaluation of the psychometric properties of a new measure of athlete burnout: The Athlete Burnout Scale. Int J Stress Manage 2018; 25: 108-123 psycnet.apa.org/
  • 18 Mellano KT, Horn TS, Mann M. Examining links between coaching behaviours and collegiate athletes’ burnout levels using a longitudinal approach. Psychol Sport Exerc 2022; 61: 102189
  • 19 Gustafsson H, Kenttä G, Hassmén P. et al. The process of burnout: A multiple case study of three elite endurance athletes. Int J Sport Psychol 2007; 38: 388-416
  • 20 Baumeister RF. Self-esteem, self-presentation, and future interaction: A dilemma of reputation. J Pers 1982; 50: 29-45
  • 21 Dahlman AS, Jonsdottir IH, Hansson C. The hypothalamo-pituitary-adrenal axis and the autonomic nervous system in burnout. Handb Clin Neurol 2021; 182: 83-94
  • 22 Jonsdottir IH, Dahlman AS. Endocrine and immunological aspects of burnout: A narrative review. Eur J Endocrinol 2019; 180: R147-R158
  • 23 De Kloet ER, Joels M, Holsboer F. Stress and the brain: From adaptation to disease. Nat Rev Neurosci 2005; 6: 463-475
  • 24 Bayes A, Tavella G, Parker G. The biology of burnout: Causes and consequences. The World J Biol Psychiatry 2021; 22: 686-698
  • 25 Allen AP, Kennedy PJ, Cryan JF. et al. Biological and physiological markers of stress in humans: Focus on the Trier Social Stress Test. Neurosci Biobehav R 2014; 38: 94-124
  • 26 Pruessner JC, Wolf OT, Hellhammer DH. et al. Free cortisol levels after awakening: A reliable biological marker for the assessment of adrenocortical activity. Life Sci 1997; 61: 2539-2549
  • 27 McEwan BS. What is the confusion with cortisol?. Chronic Stress 2019; 3: 2470547019833647
  • 28 Souza RO, Alves DL, Manoel FDA. et al. Analysis of dehydroepiandrosterone sulphate, cortisol, and testosterone levels in performance athletes affected by burnout syndrome. J Exerc Physiol Online 2018; 21: 150-156
  • 29 Morgan CA, Cho T, Hazlett G. et al. The impact of burnout on human physiology and on operational performance: A prospective study of soldiers enrolled in the combat diver qualification course. Yale J Biol Med 2002; 75: 199-205
  • 30 Moya-Albiol L, Serrano MA, Salvador A. Burnout as an important factor in the psychophysiological responses to a workday in teachers. Stress Health 2010; 26: 382-393
  • 31 Begin AS, Hata S, Berkowitz LR. et al. Biomarkers of clinician burnout. J Gen Intern Med 2022; 37: 478-479
  • 32 Melamed S, Ugarten U, Shirom A. et al. Chronic burnout, somatic arousal, and elevated salivary cortisol levels. J Psychosom Res 1999; 46: 591-598
  • 33 Deneva T, Ianakiev Y, Keskinova D. Burnout syndrome in physicians: Psychological assessment and biomarker research. Medicina (Kaunas) 2019; 55: 209
  • 34 Wingenfeld K, Schulz M, Damkroeger A. et al. Elevated diurnal salivary cortisol in nurses is associated with burnout but not with vital exhaustion. Psychoneuroendocrinology 2009; 34: 1144-1151
  • 35 Stalder T, Kirschbaum C, Kudielka BM. et al. Assessment of the cortisol awakening responses: Expert consensus guidelines. Psychoneuroendocrinology 2016; 63: 414-432
  • 36 Rothe N, Steffen J, Penz M. et al. Examination of peripheral basal and reactive cortisol levels in major depressive disorder and the burnout syndrome: A systematic review. Neurosci Biobehav R 2020; 114: 232-270
  • 37 McCanlies EC, Leppma M, Mnatsakanova A. et al. Associations of burnout with awakening and diurnal cortisol among police officers. Compr Psychoneuroendocrinol 2020; 4: 100016
  • 38 Traunmuller C, Stefitz R, Gaisbachgrabner K. et al. Psychophysiological concomitants of burnout: Evidence for different subtypes. J Psychosom Res 2019; 118: 41-48
  • 39 Sjors A, Jonsdottir IH. No alterations in diurnal cortisol profiles before and during the treatment in patients with stress-related exhaustion. Int J Occup Med Env 2015; 28: 120-129
  • 40 Marchand A, Durand P, Juster RP. et al. Workers’ psychological distress, depression, and burnout symptoms: Associations with diurnal cortisol profiles. Scand J Work Environ Health 2014; 40: 305-314 www.jstor.org/stable/43188021
  • 41 Marchand A, Juster RP, Durand P. et al. Burnout symptom sub-types and cortisol profiles: What’s burning most?. Psychoneuroendocrinology 2014; 40: 27-36
  • 42 Parent-Lamarche A, Marchand A. Work stress, personality traits, and cortisol secretion: Testing a model for job burnout. Work 2018; 60: 485-497
  • 43 Chida Y, Steptoe A. Cortisol awakening responses and psychosocial factors: A systematic review and meta-analysis. Biol Psychol 2009; 80: 265-278
  • 44 Anderson T, Wideman L, Cadegiani FA. et al. Effects of overtraining status on the cortisol awakening response – Endocrine and metabolic responses on overtraining syndrome (EROS-CAR). Int J Sport Physiol 2021; 16: 965-973
  • 45 Bellingrath S, Weigl T, Kudielka BM. Cortisol dysregulation in schoolteachers in relation to burnout, vital exhaustion, and effort-reward-imbalance. Biol Psychol 2008; 78: 104-113
  • 46 Colonnello V, Carnevali L, Russo PM. et al. Reduced recognition of facial emotional expressions in global burnout and burnout depersonalization in healthcare providers. PeerJ 2021; 9: e10610
  • 47 Osterberg K, Karlson B, Hansen AM. Cognitive performance in patients with burnout, in relation to diurnal salivary cortisol. Stress 2009; 12: 70-81
  • 48 Maslach C, Schaufeli WB, Leiter MP. Job burnout. Annu Rev Psychol 2001; 52: 397-422
  • 49 Sonnenschein M, Mommersteeg PMC, Houtveen JH. et al. Exhaustion and endocrine functioning in clinical burnout: An in-depth study using the experience sampling method. Biol Psychol 2007; 75: 176-184
  • 50 Shirom A. Job-related burnout: A review. In: Quick JC, Tetrick LE, eds. Handbook of Occupational Health Psychology. Washington, DC: American Psychological Association; 2003. psycnet.apa.org/
  • 51 Soderstrom M, Ekstedt M, Akerstedt T. Weekday and weekend patterns of diurnal cortisol, activation and fatigue among people scoring high for burnout. Scand J Work Environ Health 2006; 2: 35-40 www.sjweh.fi/article/1042
  • 52 Danhof-Pont MB, Van Veen T, Zitman FG. Biomarkers in burnout: A systematic review. J Psychosom Res 2011; 70: 505-524
  • 53 Pruessner JC, Hellhammer DH, Kirschbaum C. Burnout, perceived stress, and cortisol responses to awakening. Psychosom Med 1999; 61: 197-204
  • 54 Sjors A, Ljung T, Jonsdottir IH. Long-term follow-up of cortisol awakening response in patients treated for stress-related exhaustion. BMJ Open 2012; 2: e001091
  • 55 Davis L, Appleby R, Davis P. et al. The role of coach-athlete relationship quality in team sport athletes’ psychophysiological exhaustion: Implications for physical and cognitive performance. J Sport Sci 2018; 36: 1985-1992
  • 56 Landolt K, Maruff P, Horan B. et al. Reduced professional efficacy is associated with a blunted salivary alpha-amylase awakening response. Physiol Behav 2019; 199: 292-299
  • 57 Monfared SS, Lebeau JC, Mason J. et al. A bio-physio-psychological investigation of athletes’ burnout. Res Q Exercise Sport 2021; 92: 189-198
  • 58 Martin J, Byrd B, Hew-Butler T. et al. A longitudinal study on the psychological and physiological predictors of burnout in NCAA collegiate swimmers. J App Sport Psychol 2022; 34: 1295-1311
  • 59 De Looff PC, Cornet LJM, Embregts PJCM. et al. Associations of sympathetic and parasympathetic activity in job stress and burnout: A systematic review. PloS One 2018; 13: e0205741
  • 60 Thayer JF, Hansen AL, Johnson BH. The non-invasive assessment of autonomic influences on the heart using impedance cardiography and heart rate variability. In: Steptoe A, ed. Handbook of Behavioural Medicine. New York: Springer; 2010
  • 61 Thayer JF, Lane RD. Claude Bernard and the heart-brain connection: Further elaboration of a model of neurovisceral integration. Neurosci Biobehav R 2009; 33: 81-88
  • 62 Shaffer F, Ginsberg JP. An overview of heart rate variability metrics and norms. Front Public Health 2017; 5: 258
  • 63 Saul JP. Beat-to-beat variations of heart rate reflect modulation of cardiac autonomic outflow. Physiology 1990; 5: 32-37
  • 64 Berntson GG, Bigger JT, Eckberg DL. et al. Heart rate variability: Origins, methods, and interpretive caveats. Psychophysiology 1997; 34: 623-648
  • 65 Kalynychenko IO, Latina HO, Upsenka VM. et al. Physiological and hygienic correlates of teachers’ occupational burnout syndrome development. Wiad Lek 2021; 74: 1661-1665
  • 66 Zhang M, Liu L, Shi Y. et al. Longitudinal associations of burnout with heart rate variability in patients following acute coronary syndrome: A one-year follow-up study. Gen Hosp Psychiat 2018; 53: 59-64
  • 67 Thielmann B, Karlsen HR, Darius S. et al. Heart rate variability in different levels of burnout: Cross-sectional study of different occupational groups, heart rate variability, and burnout. J Occup Environ Med 2021; 63: e622-e630
  • 68 May RW, Seibert GS, Sanchez-Gonzalez MA. et al. School burnout and heart rate variability: Risk of cardiovascular disease and hypertension in young adult females. Stress 2018; 21: 211-216
  • 69 Lennartsson AK, Jonsdottir I, Sjors A. Low heart rate variability in patients with clinical burnout. Int J Psychophysiol 2016; 110: 171-178
  • 70 Laborde S, Mosley E, Thayer JF. Heart rate variability and cardiac vagal tone in psychophysiological research: Recommendations for experiment planning, data analysis, and data reporting. Front Psychol 2017; 8: 213
  • 71 Traunmuller C, Gaisbachgrabner K, Lackner HK. et al. Burnout of the mind – burnout of the body?. J Psychophysiol 2016; 32: 30-42
  • 72 Shi Y, Jiang R, Zhu C. et al. High job burnout predicts low heart rate variability in the working population after a first episode of acute coronary syndrome. Int J Environ Res Public Health 2021; 18: 3431 www.mdpi.com/1660-4601/18/7/3431#
  • 73 Hill LK, Sienbenbrock A, Sollers JJ. et al. Are all measures created equal? Heart rate variability and respiration. Biomed Sci Instrum 2009; 45: 71-76
  • 74 Penz M, Wekenborg MK, Pieper L. et al. The Dresden burnout study: Protocol of a prospective cohort study for the bio-psychological investigation of burnout. Int J Meth Psych Res 2018; 27: e1613
  • 75 Kanthak MK, Stalder T, Hill LB. et al. Autonomic dysregulation in burnout and depression: Evidence for the central role of exhaustion. Scand J Work Environ Health 2017; 43: 475-484 10.5271%2Fsjweh.3647
  • 76 Wekenborg MK, Hill LK, Thayer JF. et al. The longitudinal association of reduced vagal tone with burnout. Psychosom Med 2019; 81: 791-798
  • 77 Wekenborg MK, Schwerdtfeger A, Rothe N. et al. Determining the direction of prediction of the association between parasympathetic dysregulation and exhaustion symptoms. Sci Rep 2022; 12: 10648
  • 78 Schaufeli WB, Leiter MP, Maslach C. Burnout: 35 years of research and practice. Career Dev Int 2009; 14: 204-220
  • 79 De Vente W, Van Amsterdam JGC, Olff M. et al. Burnout is associated with reduced parasympathetic activity and reduced HPA axis responsiveness, predominately in males. BioMed Res Int 2015; 431725
  • 80 Kristensen TS, Borritz M, Villadsen E. et al. The Copenhagen burnout inventory: A new tool for the assessment of burnout. Work Stress 2005; 19: 192-207
  • 81 Orosz A, Federspiel A, Haisch S. et al. A biological perspective on differences and similarities between burnout and depression. Neurosci Biobehav R 2017; 73: 112-122
  • 82 Schmid RF, Thomas J. Teachers’ ambulatory heart rate variability as an outcome and moderating variable in the job demands-resources model. Anxiety Stress Coping 2020; 33: 387-402
  • 83 Barron LK, Moon MR. Impact of autonomic regulation on burnout and performance in thoracic surgery residents. JTCVS Open 2022; 11: 229-240
  • 84 Afulani PA, Ongeri L, Kinyua J. et al. Psychological and physiological stress and burnout among maternity providers in a rural county in Kenya: Individual and situational predictors. BMC Public Health 2021; 21: 453
  • 85 Gupta MD, Jha MK, Bansal A. et al. COVID-19-related burnout among healthcare workers in India and ECG based predictive machine learning model: Insights from the BRUCEE-Li study. Indian Heart J 2021; 73: 674-681
  • 86 Nutor JJ, Aborigo RA, Okiring J. et al. Individual and situational predictors of psychological and physiological stress and burnout among maternity providers in Northern Ghana. PLoS One 2022; 17: e0278457
  • 87 Dobson J, Harris B, Claytor A. et al. Selected cardiovascular and psychological changes throughout a competitive season in collegiate female swimmers. J Strength Cond Res 2020; 34: 3062-3069
  • 88 Blascovich J, Tomaka J. The biopsychosocial model of arousal regulation. In: Zanna M, ed. Advances in Experimental Social Psychology. New York: Academic Press; 1996
  • 89 Seery M. Challenge or threat? Cardiovascular indexes of resilience and vulnerability to potential stress in humans. Neurosci Biobehav R 2011; 35: 1603-1610
  • 90 Mendes WB, Park J. Neurobiological concomitants of motivational states. Advances in Motivation Science 2014; 1: 233-270
  • 91 Blascovich J. Challenge and threat. In: Elliot AJ, ed. Handbook of Approach and Avoidance Motivation. New York: Psychology Press; 2008
  • 92 McEwan BS. Stress, adaptation, and disease: Allostasis and allostatic load. Ann NY Acad Sci 1998; 840: 33-44
  • 93 Maslach C, Leiter MP. Understanding the burnout experience: Recent research and its implications for psychiatry. World Psychiatry 2016; 15: 103-111
  • 94 Jonsson P, Osterberg K, Wallergard M. et al. Exhaustion-related changes in cardiovascular and cortisol reactivity to acute psychosocial stress. Physiol Behav 2015; 151: 327-337
  • 95 Stalder T, Lupien SJ, Kudielka BM. et al. Evaluation and update of the expert consensus guidelines for the assessment of the cortisol awakening responses (CAR). Psychoneuroendocrinology 2022; 146: 105946
  • 96 Kaur S, Gupta N, Malhotra BD. Recent developments in wearable and non-wearable point-of-case biosensors for cortisol detection. Expert Rev Mol Diagn 2023; 23: 217-230
  • 97 Hogenelst K, Soeter M, Kallen V. Ambulatory measurement of cortisol: Where do we stand, and which way to follow?. Sens Bio-Sensing Res 2019; 22: 100249
  • 98 Altini M, Plews D. What is behind changes in resting heart rate and heart rate variability? A large-scale analysis of longitudinal measurements acquired in free-living. Sensors 2021; 21: 7932
  • 99 Duignan C, Doherty C, Caulfield B. et al. Single-item self-report measures of team-sport athlete wellbeing and their relationship with training load: A systematic review. J Athl Training 2020; 55: 944-953
  • 100 Gustafsson H, Madigan DJ, Lundkvist E. Burnout in athletes. In: Fuchs R, Gerber M, eds. Handbuch Stressregulation und Sport. Berlin: Springer; 2018: 489-504 link.springer.com/chapter/
  • 101 Laufer S, Engel S, Lupien S. et al. The Cortisol Assessment List (CoAL): A tool to systematically document and evaluate cortisol assessment in blood, urine, and saliva. Compr Psychoneuroendocrinol 2021; 9: 100108
  • 102 Umetani K, Singer DH, McCraty R. et al. Twenty-four-hour time domain heart rate variability and heart rate: Relations to age and gender over nine decades. J Am Coll Cardiol 1998; 31: 593-601
  • 103 Schulz P, Kirschbaum C, Pruessner J. et al. Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload. Stress Health 1998; 14: 91-97 10.1002/(SICI)1099-1700(199804)14:2%3C91::AID-SMI765%3E3.0.CO;2-S
  • 104 De Meersman RE. Heart rate variability and aerobic fitness. Am Heart J 1993; 125: 726-731
  • 105 Vargas I, Lopez-Duran N. Dissecting the impact of sleep and stress on the cortisol awakening response in young adults. Psychoneuroendocrinology 2014; 40: 10-16
  • 106 Hough J, Leal D, Scott G. et al. Reliability of salivary cortisol and testosterone to a high-intensity cycling protocol to highlight overtraining. J Sport Sci 2021; 39: 2080-2086