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Nuklearmedizin 2025; 64(03): 231-233
DOI: 10.1055/a-2543-0982
Case Report

Activation of fibroblast in intestinal Behçet’s disease shown by 68Ga-FAPI-04 PET/CT

Silu Liu 
1   Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China
2   Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China
,
Qingqing Pan
1   Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China
2   Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China
,
Hui Xu
3   Department of Gastroenterology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China (Ringgold ID: RIN34732)
,
Yaping Luo
1   Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China
2   Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China
4   State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China
› Author Affiliations
Supported by: National High Level Hospital Clinical Research Funding 2022-PUMCH-A-046,2022-PUMCH-B-070
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Keywords

intestinal Behçet’s disease - 68Ga-FAPI-04 PET/CT - Activated fibroblast


Publication History

Received: 11 February 2025

Accepted: 19 February 2025

Article published online:
26 May 2025

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  • References

  • 1 Luo Y, Pan Q, Xu H. et al. Active uptake of (68)Ga-FAPI in Crohn’s disease but not in ulcerative colitis. Eur J Nucl Med Mol Imaging 2021; 48: 1682-1683
    CrossrefPubMedSearch in Google Scholar
  • 2 Fitzgerald AA, Weiner LM. The role of fibroblast activation protein in health and malignancy. Cancer and Metastasis Reviews 2020; 39: 783-803
    CrossrefPubMedSearch in Google Scholar
  • 3 D’Alessio S, Ungaro F, Noviello D. et al. Revisiting fibrosis in inflammatory bowel disease: the gut thickens. Nat Rev Gastroenterol Hepatol 2022; 19: 169-184
    CrossrefPubMedSearch in Google Scholar
  • 4 Vaiopoulos AG, Sfikakis PP, Kanakis MA. et al. Gastrointestinal manifestations of Behçet’s disease: advances in evaluation and management. Clin Exp Rheumatol 2014; 32: S140-148
    PubMedSearch in Google Scholar
  • 5 Valenti S, Gallizzi R, De Vivo D. et al. Intestinal Behçet and Crohn’s disease: two sides of the same coin. Pediatr Rheumatol Online J 2017; 15: 33
    CrossrefPubMedSearch in Google Scholar