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DOI: 10.1055/a-2575-1211
Keystone Perforator Island Advancement Flap as Another Option for Closure after Radical Excision of Axillary Hidradenitis Suppurativa
Funding None.

Abstract
Surgical treatment of axillary hidradenitis suppurativa (HS) requires wide excision followed by definitive wound closure to not limit shoulder function. An international prospective study was undertaken to compare how a keystone perforator island advancement flap can be a reliable solution. Independently, two Transatlantic institutions, from 2019 to 2024, surgically resected axillary HS followed by a keystone perforator flap for defect management. A total of 23 patients were treated, including 4 with bilateral disease, employing 27 total flaps that permitted the comparison of demographic data, Hurley disease stage, flap viability and complications, need for secondary surgeries, duration of treatment, and functional outcome. Demographic data in both countries was similar with regard to mean age, female preponderance, presence of obesity, and prior means of treatment. Surgical treatment was not limited in either country only to Hurley stage III individuals. In Romania, 6/11 (54.5%) compared to 3/12 (25.0%) of U.S. patients were classified as Hurley stage II. No flap necrosis was observed, allowing unrestricted shoulder mobility within 3.5 (2–4) months in Romania, but more slowly by 4.4 (3–9) months in the United States. All complications were minor, occurring in 11 (43.5%) patients, albeit three times more frequently in the United States. Overall, the most common problem was lesser curvature dehiscence (63.6%). No disease recurrences were noted. The keystone perforator island advancement flap is a safe, rapid, and simple local flap option for the closure of the axillary defect after the excision of HS. The learning curve was straightforward, so reconstructive surgeons can readily adapt to utilize this approach.
Authors' Contributions
Conceptualization, actual surgery for those patients included in their country, and writing, including original draft, review, and editing, was done by all authors. The video itself was re-edited by G.G.H.
Ethical Approval
Not applicable.
Patient Consent
Informed consent was obtained from all patients to appropriately allow the use of their clinical photographs or other data for this research, educational, and publication purposes.
Publication History
Received: 25 March 2024
Accepted: 31 March 2025
Article published online:
23 July 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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References
- 1
Taylor EM,
Hamaguchi R,
Kramer KM,
Kimball AB,
Orgill DP.
Plastic surgical management of hidradenitis suppurativa. Plast Reconstr Surg 2021;
147 (03) 479-491
MissingFormLabel
- 2
Jandali S,
Mirzabeigi MN,
Fosnot J,
Low DW.
Thoracodorsal artery perforator flaps and muscle-sparing latissimus dorsi myocutaneous
flaps for the treatment of axillary hidradenitis. Ann Plast Surg 2012; 69 (04) 371-375
MissingFormLabel
- 3
Jemec GBE.
Clinical practice. Hidradenitis suppurativa. N Engl J Med 2012; 366 (02) 158-164
MissingFormLabel
- 4
Falola RA,
DeFazio MV,
Anghel EL,
Mitnick CDB,
Attinger CE,
Evans KK.
What heals hidradenitis suppurativa: Surgery, immunosuppression, or both?. Plast Reconstr
Surg 2016; 138 (3 Suppl): 219S-229S
MissingFormLabel
- 5
Marchesi A,
Amendola F,
Garieri P,
Steinberger Z,
Vaienti L.
Wide local excisions and pedicled perforator flaps in hidradenitis suppurativa: A
study of quality of life. Ann Plast Surg 2021; 86 (02) 201-205
MissingFormLabel
- 6
Virág TH,
Kadar IA,
Matei IR,
Georgescu AV.
Surgical management of hidradenitis suppurativa with keystone perforator island flap.
Injury 2020; 51 (Suppl. 04) S41-S47
MissingFormLabel
- 7
Marchesi A,
Marcelli S,
Zingaretti N,
Parodi PC,
Vaienti L.
Pedicled thoracodorsal artery perforator and muscle-sparing latissimus dorsi flaps
in the axillary reconstruction after hidradenitis suppurativa excision: Functional
and aesthetic issues. Ann Plast Surg 2018; 81 (06) 694-701
MissingFormLabel
- 8
La Padula S,
Pensato R,
Pizza C.
et al.
The thoracodorsal artery perforator flap for the treatment of hidradenitis suppurativa
of the axilla: A prospective comparative study. Plast Reconstr Surg 2023; 152 (05)
1105-1116
MissingFormLabel
- 9
Hamaguchi R,
Wearda TL,
Volk AS.
et al.
Surgical management of hidradenitis suppurativa: A two-center retrospective study.
Plast Reconstr Surg 2022; 150 (05) 1115-1127
MissingFormLabel
- 10
Behan FC.
The keystone design perforator island flap in reconstructive surgery. ANZ J Surg 2003;
73 (03) 112-120
MissingFormLabel
- 11
Hallock GG.
The use of smartphone thermography to more safely unmask and preserve circulation
to keystone advancement flaps in the lower extremity. Injury 2020; 51 (Suppl. 04)
S121-S125
MissingFormLabel
- 12
Elliott J,
Chui K,
Rosa N,
Reffell L,
Jemec B.
Hidradenitis suppurativa: A review of post-operative outcomes. J Plast Reconstr Aesthet
Surg 2021; 74 (03) 644-710
MissingFormLabel
- 13
Thomson DR,
Saltrese S,
Mehdi S.
Modified posterior arm flap for axillary hidradenitis suppurativa. Ann Plast Surg
2022; 88: 84-87
MissingFormLabel
- 14
Lipshutz H.
Closure of axillary hidradenitis defects with local triangular flaps. Plast Reconstr
Surg 1974; 53 (06) 677-679
MissingFormLabel
- 15
Schwabegger AH,
Herczeg E,
Piza H.
The lateral thoracic fasciocutaneous island flap for treatment of recurrent hidradenitis
axillaris suppurativa and other axillary skin defects. Br J Plast Surg 2000; 53 (08)
676-678
MissingFormLabel
- 16
Mehrotra S.
Island thoracodorsal artery perforator-based V-Y advancement flap after radical excision
of axillary hidradenitis. Ann Plast Surg 2015; 74 (01) 133-134
MissingFormLabel
- 17
Rehman N,
Kannan RY,
Hassan S,
Hart NB.
Thoracodorsal artery perforator (TAP) type I V-Y advancement flap in axillary hidradenitis
suppurativa. Br J Plast Surg 2005; 58 (04) 441-444
MissingFormLabel
- 18
Hallock GG.
Island thoracodorsal artery perforator-based V-Y advancement flap after radical excision
of axillary hidradenitis. Ann Plast Surg 2013; 71 (04) 390-393
MissingFormLabel
- 19
Alabdulkareem M,
Berkane Y,
Le Bras E.
et al.
Axillary hidradenitis suppurativa: A comparison between two perforator flap reconstructive
approaches after radical surgical management. Plast Reconstr Surg Glob Open 2023;
11 (10) e5301
MissingFormLabel
- 20
Mohan AT,
Rammos CK,
Akhavan AA.
et al.
Evolving concepts of keystone perforator island Flaps (KPIF): Principles of perforator
anatomy, design modifications, and extended clinical applications. Plast Reconstr
Surg 2016; 137 (06) 1909-1920
MissingFormLabel
- 21
Mohan AT,
Sur YJ,
Zhu L.
et al.
The concepts of propeller, perforator, keystone, and other local flaps and their role
in the evolution of reconstruction. Plast Reconstr Surg 2016; 138 (04) 710e-729e
MissingFormLabel