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DOI: 10.1055/a-2674-7109
Clinical Decision-Making and Use of Clinical Decision Support When Clinicians are Fatigued in an Emergency Department: A Qualitative Study
Authors
Funding This study was supported by the National Library of Medicine under award number: R21 LM013909 (principal investigator: M.O.).

Abstract
Background
Clinicians' occupational fatigue can lead to suboptimal decisions that do not align with evidence-based guidelines or patient needs.
Objectives
Examining the effects of occupational fatigue on (1) clinical decision making and (2) the use of clinical decision support (CDS) in a pediatric emergency department (ED).
Methods
We interviewed 30 pediatric ED clinicians from a single site. Clinicians included physicians and advanced practice practitioners. The interviews were semi-structured and guided by the dual-processing model. Data were qualitatively analyzed.
Results
Four main themes emerged from our analysis: (1) fatigue is a dynamic state and has multiple reasons; (2) fatigue affects decision-making in ED care; (3) fatigue affects the use of CDS; (4) fatigue affects a clinician's productivity and outcomes. We developed a conceptual framework that highlights the effects of fatigue on outcomes in the ED setting.
Conclusion
In EDs, fatigue is inevitable because of high clinical acuity and the rapid pace of decision-making. Our study highlighted an important need in EDs to support narrative decision-making. Narrative decision-making requires clinicians to make analytical decisions, as opposed to relying on intuition in providing care. Organizational redesign and informatics-based interventions initiatives could be useful to mitigate the effects of fatigue. Rigorous evaluation approaches that account for clinicians' fatigue would improve the usability and usefulness of organizational interventions (e.g., CDS) that improve quality and safety.
Keywords
dual processing - requirements analysis and design - implementation and deployment - burnout - sociotechnical aspects of information technologyProtection of Human and Animal Subjects
The study was performed in compliance with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects and was reviewed by Colorado Multiple Institutional Review Board (COMIRB).
Publication History
Received: 23 March 2025
Accepted: 01 August 2025
Accepted Manuscript online:
04 August 2025
Article published online:
17 September 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
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