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DOI: 10.1055/a-2680-4309
Skincare Regimens for Men: Medical-Grade Solutions

Abstract
Aims and Background
Despite growing awareness of skin health, male patients remain less likely to engage in daily skincare or pursue cosmetic dermatologic care. This review provides an evidence-based framework for understanding male-specific skin biology, behavior, and treatment strategies to improve outcomes and adoption.
Anatomy
Male skin is thicker, oilier, more acidic, and contains denser terminal hairs and collagen than female skin. It has increased transepidermal water loss, a more robust vascular supply, and higher androgen-driven glandular activity, all of which influence barrier integrity, aging, and treatment response.
Patient Selection
Successful engagement of male patients requires understanding their goals, lifestyle, and psychological drivers. Men prefer performance-focused language, streamlined routines, and clear functional benefits.
Techniques
Tailored regimens emphasizing minimal steps, multifunctional products, and tolerable formulations are key. Interventions must account for unique features such as thicker dermis and distinct patterns of aging and facial musculature.
Current and Future Development
Emerging therapies such as exosome-based products, male-focused marketing, and gender-specific formulation advances support increased adoption and efficacy.
Conclusion and Clinical Relevance
Dermatologists must consider the biologic and behavioral distinctions of male skin to enhance prevention, adherence, and treatment outcomes. Sex-specific strategies can improve long-term skin health and aesthetics.
Declaration of GenAI Use
During the writing process of this article, the authors used OpenAI's ChatGPT only in the structure of the outline and citation formatting. The authors have reviewed and edited the text and take full responsibility for the content of the article.
Publication History
Received: 18 July 2025
Accepted: 10 August 2025
Article published online:
01 September 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
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