Appl Clin Inform 2025; 16(05): 1850-1861
DOI: 10.1055/a-2765-6842
Research Article

A Rule-Based Automated Triage Model Using Natural Language Processing for Pain Medicine—Development and Implementation

Autor*innen

  • Lan Jiang

    1   Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, United States
  • Yu-Li Huang

    1   Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, United States
  • Jungwei Fan

    2   Department of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, Minnesota, United States
  • Christy L. Hunt

    3   Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, United States
  • Jason S. Eldrige

    3   Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, United States
  • Lezli Kuster

    1   Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, United States
  • Maribeth A. Jensen

    1   Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, United States
  • Sahil Gupta

    3   Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, United States

Abstract

Background

Pain medicine triage plays a crucial role in ensuring patients receive timely and appropriate care by scheduling them to the most suitable treatment path. However, the absence of standardized triage protocols in pain medicine often leads to inefficiencies, including delay of care and wastage of healthcare resources.

Objective

This study aims to develop a rule-based automated referral triage system leveraging information from patients' medical notes for scheduling patients to specific procedures in the pain medicine department.

Methods

The proposed triage system, grounded in the knowledge and expertise of clinical providers, processed referral order comments and referring provider notes by iteratively refining the Natural Language Processing (NLP) rules and post-processing rules through intensively reviewing 76 patients. A post-processing regression model was incorporated to further enhance the accuracy. To ensure alignment with real-world practices, the system was integrated into an electronic health record (EHR) platform for real-time application, streamlining scheduling workflows and enhancing usability in daily clinical settings.

Results

After three iterations, the proposed NLP and post-processing rules improved accuracy from 76.3 to 80.3% compared to machine learning (ML) approaches in the preliminary study. The post-processing model further increased accuracy to 84.2%. The implementation accuracy of 200 cases for the first 3 months was consistent with our prediction at 83.5%, which concluded that the improvement over ML models (p-value = 0.018) was statistically significant at 95% significance level.

Conclusion

This study demonstrates the feasibility and benefits of a knowledge-driven approach to referral triage in specialized medical fields. It lays a foundation for others in building similar triaging solutions to other specialties.

Protection of Human and Animal Subjects

Our Institutional Review Board (IRB) acknowledges that based on the responses submitted for this study through the Human Subjects Research Wizard tool, and in accordance with the Code of Federal Regulations, 45 CFR 46.102, the study does not require IRB review.




Publikationsverlauf

Eingereicht: 11. April 2025

Angenommen: 04. Dezember 2025

Artikel online veröffentlicht:
18. Dezember 2025

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