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Horm Metab Res 1975; 7(4): 305-309
DOI: 10.1055/s-0028-1093719
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© Georg Thieme Verlag KG Stuttgart · New York

The Contribution of the Pancreas and the Intestine to the Regulation of Lipolysis in Birds - I. Existence of Highly Potent Lipolytic Factors in Ileum Extracts

E.  Krug , P.  Mialhe
  • Laboratoire de Physiologie Générale, Université Louis Pasteur, Strasbourg, France (ERA 188, CNRS and INSERM)
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Publication Date:
23 December 2008 (online)

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Abstract

Duck intestinal extracts were separated into three main peaks of proteins by chromatography on P6 BioGel columns. The first, which cross reacted with glucagon antibodies, gut "GLI", did not stimulate lipolysis in isolated chicken adipocytes. Both second and third peaks, corresponding to smaller molecular-size peptides were even more lipolytic than pancreatic glucagon.

Key words

Glucagon - Gut "GLI" - Gut Peptides - Lipolysis - Isolated Chicken Fat Cells

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