Horm Metab Res 1974; 6(5): 376-380
DOI: 10.1055/s-0028-1093828

© Georg Thieme Verlag KG Stuttgart · New York

Effect of Insulin on the Materno-Fetal Transfer of Glucose in the Rat

Francoise  Rabain , L.  Picon
  • Laboratoire de Physiologie animale, Université Paris 7, Paris 5e, France
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Publication History

Publication Date:
07 January 2009 (online)


14C glucose incorporation, as studied in 20 1/2 and 21 1/2 day old rat fetuses after a glucose 14C injection into the mother, is increased by insulin whereas it is depressed by anti-insulin serum injection into the fetus. The data suggest that rat fetal tissues are already insulin sensitive at the end of the gestation and that fetal insulin itself plays a role in the control of materno-fetal transfer of glucose.